Evidence map›Paper›PMID 33796187›Full record

ArticleThe Pan African medical journal2020

[National profile of early warning indicators of HIV pharmaco-resistance in Cameroon].

Serge Clotaire Billong, Joseph Fokam, Calixte Ida Penda, Ernest Anaba Mvilongo, Raoul Fodjo, Arlette Messeh, Jean de Dieu Anoubissie, Cyprien Kegne, Gildas Nguekam, Yannick Aimé Batamack and 6 more

Abstract readMulticenter Study
In one paragraph

Article in The Pan African medical journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Serge Clotaire BillongDépartement de Santé Publique, Faculté de Médecine et des Sciences Biomédicales, Université de Yaoundé I, Yaoundé, Cameroun.
Joseph FokamDépartement de Santé Publique, Faculté de Médecine et des Sciences Biomédicales, Université de Yaoundé I, Yaoundé, Cameroun.
Calixte Ida PendaHôpital de Jour, Hôpital Laquintinie de Douala, Douala, Cameroun.
Ernest Anaba MvilongoGroupe Technique Central, Comité Nationale de Lutte Contre le SIDA, Yaoundé, Cameroun.
Raoul FodjoGroupe Technique Central, Comité Nationale de Lutte Contre le SIDA, Yaoundé, Cameroun.
Arlette MessehGroupe Technique Central, Comité Nationale de Lutte Contre le SIDA, Yaoundé, Cameroun.
Jean de Dieu AnoubissieGroupe Technique Central, Comité Nationale de Lutte Contre le SIDA, Yaoundé, Cameroun.
Cyprien KegneGroupe Technique Central, Comité Nationale de Lutte Contre le SIDA, Yaoundé, Cameroun.
Gildas NguekamDivision de la Recherche Opérationnelle en Santé, Ministère de la Santé Publique, Yaoundé, Cameroun.
Yannick Aimé BatamackGroupe Technique Central, Comité Nationale de Lutte Contre le SIDA, Yaoundé, Cameroun.
Edson Joan BillongFaculté de Médecine, Université d'Antananarivo, Antananarivo, Madagascar.
Pamela Reine MoutapamGroupe Technique Central, Comité Nationale de Lutte Contre le SIDA, Yaoundé, Cameroun.
Alexis NdjoloDépartement de Santé Publique, Faculté de Médecine et des Sciences Biomédicales, Université de Yaoundé I, Yaoundé, Cameroun.
Leonard BononoGroupe Technique Central, Comité Nationale de Lutte Contre le SIDA, Yaoundé, Cameroun.
Jean Bosco ElatGroupe Technique Central, Comité Nationale de Lutte Contre le SIDA, Yaoundé, Cameroun.
Anne Cécilé Zoung-Kanyi BissekDépartement de Santé Publique, Faculté de Médecine et des Sciences Biomédicales, Université de Yaoundé I, Yaoundé, Cameroun.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionsince the launch of the "Treatment for All in Cameroon" strategy in 2015, an acceleration plan for antiretroviral (ARV) therapy in Cameroon was implemented, with remarkable progresses. These efforts were accompanied by the risk of developing HIV drug resistance. Then, the World Health Organization (WHO) proposed surveillance of early warning indicators (IAP) for HIV drug resistance. The purpose of this study was to assess the national HIV Drug Resistance Early Warning Indicators (EWI) in Cameroon.

methodswe conducted a retrospective study in the ten regions of Cameroon in December 2017 to evaluate the six EWIs recommended by the WHO in 68 randomly selected HIV care sites. The reporting period ranged from July 2016 to June 2017.

resultsnational scores were: drug withdrawal within the estimated time frame (EWI1): 66%; retention on antiretroviral therapy 12 months after treatment initiation (EWI2): 66%; stock-out of antiretroviral drugs over a 12-month period (EWI3): 53%; viral load testing coverage (CV) (EWI4): 10%; coverage suppression after 12 months of antiretroviral therapy (EWI5): 73% and practices for ARV drug delivery (EWI6): (100%). Regional scores were similar.

conclusionthe evaluation of EWI in Cameroon is limited and requires urgent interventions, primarily viral load testing coverage, optimal ARVs management and patient´s adherence.

Indexed as

Viral LoadAnti-HIV AgentsCameroonDrug Resistance, ViralHIV InfectionsHumansRetrospective StudiesTime FactorsAnti-HIV AgentsCameroonEarly warning indicatorsHIV drug resistance

Identifiers

PMID33796187
PMCPMC7992409

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.