ArticleFrontiers in immunology2021
Serum Neurofilament Light and GFAP Are Associated With Disease Severity in Inflammatory Disorders With Aquaporin-4 or Myelin Oligodendrocyte Glycoprotein Antibodies.
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In one paragraph
Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 3 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed, 3 pooled it
7.4field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 3 syntheses or guidelines pooled it, 73 citations in OpenAlex.
- Biomarkers to predict relapse in myelin oligodendrocyte glycoprotein antibody-associated disease: a systematic review and meta-analysis.Journal of neurology, neurosurgery, and psychiatry · 2026Pooled it
- Clinical applications and diagnostic research of GFAP and NfL in MS and NMOSD: a meta-analysis.BMC immunology · 2025Pooled it
- The Role of Glial Fibrillary Acidic Protein as a Biomarker in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder: A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2024Pooled it
- Serum neurofilament light chain levels at attack predict post-attack disability worsening and are mitigated by inebilizumab: analysis of four potential biomarkers in neuromyelitis optica spectrum disorder.Journal of neurology, neurosurgery, and psychiatry · 2023Trial
- Serum GFAP and Age Accurately Distinguish AQP4-IgG Positive and Double Seronegative NMOSD From MOGAD After a Recent Attack.European journal of neurology · 2026Article
- Intrathecal immunoglobulin production in the diagnosis, prognosis, and monitoring of autoimmune diseases of the central nervous system.Journal of translational autoimmunity · 2026Review
- Neuroglial markers of damage in autoimmune neurology.Therapeutic advances in neurological disorders · 2026Review
- Biomarkers for myelin oligodendrocyte glycoprotein-associated disease: recent advances and future.Frontiers in immunology · 2026Review
- Longitudinal assessment of sNfL and sGFAP in severe NMOSD treated with allogeneic stem cell transplantation.Frontiers in immunology · 2026Article
- Plasma NfL and GFAP as Candidate Biomarkers of Disease Activity in NMOSD and MOGAD.Medicina (Kaunas, Lithuania) · 2025Article
- Neurofilament Biomarkers in Neurology: From Neuroinflammation to Neurodegeneration, Bridging Established and Novel Analytical Advances with Clinical Practice.International journal of molecular sciences · 2025Review
- MOGAD: A Shifting Landscape-From Pathogenesis to Personalised Management, Global Perspectives and Latin American Insights.Biomedicines · 2025Review
- Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease: Pathophysiology, Clinical Patterns, and Therapeutic Challenges of Intractable and Severe Forms.International journal of molecular sciences · 2025Review
- Cerebrospinal 14-3-3 Protein Levels as a Neuroaxonal Biomarker in Aquaporin-4 Antibody-Positive Neuromyelitis Optica Spectrum Disorder.Neurology(R) neuroimmunology & neuroinflammation · 2025Article
- Factors for Rituximab Refractoriness in AQP4-IgG+ NMOSD: A Cohort Study.Annals of clinical and translational neurology · 2025Article
- Serum GFAP and NFL as biomarkers for disease activity, severity and disability in NMOSD.Journal of neurology · 2025Article
- Extracellular Vesicle Marker Changes Associated With Disease Activity in Relapsing-Remitting Multiple Sclerosis.Neurology(R) neuroimmunology & neuroinflammation · 2025Article
- Role of soluble biomarkers in treating multiple sclerosis and neuroinflammatory conditions.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Review
- Long-Term Clinical and Biological Prognostic Factors of Anti-NMDA Receptor Encephalitis in Children.Neurology(R) neuroimmunology & neuroinflammation · 2025Observational
- Blood-Based Biomarkers for Identifying Disease Activity in AQP4-IgG-Positive Neuromyelitis Optica Spectrum Disorder.JAMA neurology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 3 institutions in 1 country.
Xuechun ChangDepartment of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Wenjuan HuangDepartment of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Liang WangDepartment of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Jingzi ZhangBaoDepartment of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Lei ZhouDepartment of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Chuanzhen LuDepartment of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Min WangDepartment of Ophthalmology and Vision Science, Eye and ENT Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Jian YuDepartment of Ophthalmology and Vision Science, Eye and ENT Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Haiqing LiDepartment of Radiology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Yuxin LiDepartment of Radiology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Chongbo ZhaoDepartment of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Jiahong LuDepartment of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Chao QuanDepartment of Neurology, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Fudan University · CNHuashan Hospital · CNEye & ENT Hospital of Fudan University · CN
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Severity of Illness IndexAdultAquaporin 4AutoantibodiesBiomarkersCase-Control StudiesCross-Sectional StudiesFemaleGlial Fibrillary Acidic ProteinHumansMaleMiddle AgedMultiple Sclerosis, Relapsing-RemittingMyelin-Oligodendrocyte GlycoproteinNeurofilament ProteinsNeuromyelitis OpticaAQP4 protein, humanAquaporin 4AutoantibodiesBiomarkersGFAP protein, humanGlial Fibrillary Acidic ProteinMOG protein, humanMyelin-Oligodendrocyte Glycoproteinneurofilament protein LNeurofilament Proteinsaquaporin-4glial fibrillary acidic proteinmyelin oligodendrocyte glycoproteinneurofilament lightneuromyelitis optica spectrum disorder
Identifiers
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.