Evidence map›Paper›PMID 33796055›Full record

ArticleFrontiers in psychology2021

Psychedelic Harm Reduction and Integration: A Transtheoretical Model for Clinical Practice.

Ingmar Gorman, Elizabeth M Nielson, Aja Molinar, Ksenia Cassidy, Jonathan Sabbagh

2 registry-linked trialsAbstract read
In one paragraph

Article in Frontiers in psychology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 56 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07369102 phase4recruitingnot on this mapstarted 2026, after this paper: background citation

Esketamine With or Without Psychedelic Preparation and Integration for Treatment-Resistant Depression: A Randomized Controlled Trial

TypeinterventionalSponsorUniversity of Puerto RicoRan2026 to 2026Enrolled20ConditionsTreatment-resistant Depression (TRD)ArmsEsketamine hydrochloride (intranasal), Integration Therapy
NCT07737990 naenrolling by invitationnot on this mapstarted 2026, after this paper: background citation

Psilocybin-Assisted Group Integration Psychotherapy for Treatment-Resistant Depression

TypeinterventionalSponsorJoshua RosenblatRan2026 to 2030Enrolled65ConditionsTreatment-resistant Depression (TRD)ArmsGroup integration therapy
3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Impact of psilocybin on cognitive function: A systematic review.Psychiatry and clinical neurosciences · 2024
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  3. A contemporary exploration of motivations and practices of psychedelic use among emerging adult cannabis users in the United States: A qualitative analysis.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ingmar GormanMAPS Public Benefit Corp, Santa Cruz, CA, United States.
Elizabeth M NielsonMAPS Public Benefit Corp, Santa Cruz, CA, United States.
Aja MolinarTodman Psychopathology Lab, Psychology Department, New School for Social Research, New York, NY, United States.
Ksenia CassidyTodman Psychopathology Lab, Psychology Department, New School for Social Research, New York, NY, United States.
Jonathan SabbaghJourney Clinical, Inc. Dover, DE, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psychedelic Harm Reduction and Integration (PHRI) is a transtheoretical and transdiagnostic clinical approach to working with patients who are using or considering using psychedelics in any context. The ongoing discussion of psychedelics in academic research and mainstream media, coupled with recent law enforcement deprioritization of psychedelics and compassionate use approvals for psychedelic-assisted therapy, make this model exceedingly timely. Given the prevalence of psychedelic use, the therapeutic potential of psychedelics, and the unique cultural and historical context in which psychedelics are placed, it is important that mental health providers have an understanding of the unique motivations, experiences, and needs of people who use them. PHRI incorporates elements of harm reduction psychotherapy and psychedelic-assisted psychotherapy, and can be applied in both brief and ongoing psychotherapy interactions. PHRI represents a shift away from assessment limited to untoward outcomes of psychedelic use and abstinence-based addiction treatment paradigms and toward a stance of compassionate, destigmatizing acceptance of patients' choices. Considerations for assessment, preparation, and working with difficult experiences are presented.

Indexed as

harm reductionintegrationMDMAPHRIpreparationpsilocybinpsychedelicspsychotherapy

Identifiers

PMID33796055
PMCPMC8008322

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.