Evidence map›Paper›PMID 33795729›Full record

ArticleScientific reports2021

Statistical shape modeling of the talocrural joint using a hybrid multi-articulation joint approach.

Amy L Lenz, Nicola Krähenbühl, Andrew C Peterson, Rich J Lisonbee, Beat Hintermann, Charles L Saltzman, Alexej Barg, Andrew E Anderson

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
5.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Morphological analysis of ankle joint space width.Surgical and radiologic anatomy : SRA · 2025
    Article
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  15. Article
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  17. Ankle osteoarthritis: Toward new understanding and opportunities for prevention and intervention.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2024
    Review
  18. Article
  19. HumanJournal of the Royal Society, Interface · 2024
    Article
  20. OPTIMIZATION-DRIVEN STATISTICAL MODELS OF ANATOMIES USING RADIAL BASIS FUNCTION SHAPE REPRESENTATION.Proceedings. IEEE International Symposium on Biomedical Imaging · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 3 countries.

Amy L Lenz *Department of Orthopaedics, University of Utah, Salt Lake City, 84108, USA.
Nicola Krähenbühl *Department of Orthopaedics, Kantonsspital Baselland, 4410, Liestal, Switzerland.
Andrew C PetersonDepartment of Orthopaedics, University of Utah, Salt Lake City, 84108, USA.
Rich J LisonbeeDepartment of Orthopaedics, University of Utah, Salt Lake City, 84108, USA.
Beat HintermannDepartment of Orthopaedics, Kantonsspital Baselland, 4410, Liestal, Switzerland.
Charles L SaltzmanDepartment of Orthopaedics, University of Utah, Salt Lake City, 84108, USA.
Alexej BargDepartment of Orthopaedics, University of Utah, Salt Lake City, 84108, USA.
Andrew E AndersonDepartment of Orthopaedics, University of Utah, Salt Lake City, 84108, USA. andrew.anderson@hsc.utah.edu.
University of Utah · USKantonsspital Baselland · CH

Funding

TRD - VisualizationP41GM103545 · NIGMS · UNIVERSITY OF UTAH · PI JOHNSON, CHRISTOPHER R., MACLEOD, ROB S. · 2012 to 2019
$9.7M
Finite Elements For Biomechanics And BiophysicsR01GM083925 · NIGMS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI GERARD A. ATESHIAN, JEFFREY A. WEISS · 2008 to 2026
$7.6M
Population-Based Shape and Biomechanical Analysis of Hip PathoanatomyR01EB016701 · NIBIB · UNIVERSITY OF UTAH · PI ANDERSON, ANDREW EDWARD · 2013 to 2023
$3.6M
ShapeWorks in the CloudR01AR076120 · NIAMS · UNIVERSITY OF UTAH · PI ELHABIAN, SHIREEN YOUSSEF · 2019 to 2024
$2.7M
New 3D and 4D Image-Based Clinical Measures of Atrial Structural and Functional Remodeling in Atrial FibrillationR01HL135568 · NHLBI · UNIVERSITY OF UTAH · PI CATES, JOSHUA E, ELHABIAN, SHIREEN YOUSSEF · 2017 to 2020
$1.4M
ShapeWorksStudio: An Integrative, User-Friendly, and Scalable Suite for Shape Representation and AnalysisU24EB029011 · NIBIB · UNIVERSITY OF UTAH · PI ELHABIAN, SHIREEN YOUSSEF · 2019 to 2023
$1.4M
In Vivo Arthrokinematics of Total Ankle Replacement and Ankle ArthrodesisR21AR069773 · NIAMS · UNIVERSITY OF UTAH · PI ANDERSON, ANDREW EDWARD · 2017 to 2018
$367k
NHLBI NIH HHS R01 HL135568NIAMS NIH HHS R01 AR076120NIAMS NIH HHS R21 AR069773NIBIB NIH HHS R01 EB016701NIBIB NIH HHS U24 EB029011NIGMS NIH HHS P41 GM103545NIGMS NIH HHS R01 GM083925
6 · The paper itself

Abstract

Historically, conventional radiographs have been the primary tool to morphometrically evaluate the talocrural joint, which is comprised of the distal tibia, distal fibula, and proximal talus. More recently, high-resolution volumetric imaging, including computed tomography (CT), has enabled the generation of three-dimensional (3D) reconstructions of the talocrural joint. Weightbearing cone-beam CT (WBCT) technology provides additional benefit to assess 3D spatial relationships and joint congruency while the patient is load bearing. In this study we applied statistical shape modeling, a computational morphometrics technique, to objectively quantify anatomical variation, joint level coverage, joint space distance, and congruency at the talocrural joint. Shape models were developed from segmented WBCT images and included the distal tibia, distal fibula, and full talus. Key anatomical variation across subjects included the fibular notch on the tibia, talar trochlea sagittal plane rate of curvature, tibial plafond curvature with medial malleolus prominence, and changes in the fibular shaft diameter. The shape analysis also revealed a highly congruent talocrural joint with minimal inter-individual morphometric differences at the articular regions. These data are helpful to improve understanding of ankle joint pathologies and to guide refinement of operative treatments.

Indexed as

Tomography, X-Ray ComputedAdultAnkle JointBiomechanical PhenomenaFemaleHumansImage Processing, Computer-AssistedMaleMiddle AgedModels, AnatomicModels, StatisticalModels, TheoreticalMotionPrincipal Component AnalysisReproducibility of ResultsTibia

Identifiers

PMID33795729
PMCPMC8016855
OpenAlexW3151960447

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.