ArticleScientific reports2021
The virome of German bats: comparing virus discovery approaches.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Viral Co-Infection in Bats: A Systematic Review.Viruses · 2023Pooled it
- Detection of coronaviruses in insectivorous bats of Fore-Caucasus, 2021.Scientific reports · 2023Pooled it
- Global status, bias risks, and ecological integration of wild bat and rodent virome research.One health (Amsterdam, Netherlands) · 2026Review
- Review
- No longer uncertain: the validation of tenebrionid insects as hosts ofThe Journal of general virology · 2026Article
- Characterizing the parvovirome of Swazi bats: novel species, highly divergent lineages, endogenous viral elements, and taxonomic challenges.Virus evolution · 2026Article
- Bacterial Composition Across Bat Species: A Human Health Perspective.Animals : an open access journal from MDPI · 2025Review
- Deriving fibroblast cell lines from wing-punch biopsies of Australian eastern bent-winged bats (PeerJ · 2025Article
- Defined domains and cleavage determine the diverse functions of piscine myocarditis virus p33 protein.Frontiers in microbiology · 2025Article
- Individual virome analysis reveals the general co-infection of mammal-associated viruses with SARS-related coronaviruses in bats.Virologica Sinica · 2024Article
- Metagenomic sequencing sheds light on microbes putatively associated with pneumonia-related fatalities of white-tailed deer (Microbial genomics · 2024Article
- Metagenomic of Liver Tissue Identified at Least Two Genera of Totivirus-like Viruses inMicroorganisms · 2024Article
- Unraveling the genomic landscape of piscine myocarditis virus: mutation frequencies, viral diversity and evolutionary dynamics in Atlantic salmon.Virus evolution · 2024Article
- Substantial viral and bacterial diversity at the bat-tick interface.Microbial genomics · 2023Article
- Investigation of the Virome and Characterization of Issyk-Kul Virus from SwedishPathogens (Basel, Switzerland) · 2022Article
- Article
- A framework for testing the impact of co-infections on host gut microbiomes.Animal microbiome · 2022Review
- Characterization ofViruses · 2022Article
- Diversity and evolution of the animal virome.Nature reviews. Microbiology · 2022Review
- Zoonotic disease and virome diversity in bats.Current opinion in virology · 2022Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bats are known to be reservoirs of several highly pathogenic viruses. Hence, the interest in bat virus discovery has been increasing rapidly over the last decade. So far, most studies have focused on a single type of virus detection method, either PCR, virus isolation or virome sequencing. Here we present a comprehensive approach in virus discovery, using all three discovery methods on samples from the same bats. By family-specific PCR screening we found sequences of paramyxoviruses, adenoviruses, herpesviruses and one coronavirus. By cell culture we isolated a novel bat adenovirus and bat orthoreovirus. Virome sequencing revealed viral sequences of ten different virus families and orders: three bat nairoviruses, three phenuiviruses, one orbivirus, one rotavirus, one orthoreovirus, one mononegavirus, five parvoviruses, seven picornaviruses, three retroviruses, one totivirus and two thymoviruses were discovered. Of all viruses identified by family-specific PCR in the original samples, none was found by metagenomic sequencing. Vice versa, none of the viruses found by the metagenomic virome approach was detected by family-specific PCRs targeting the same family. The discrepancy of detected viruses by different detection approaches suggests that a combined approach using different detection methods is necessary for virus discovery studies.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.