Evidence map›Paper›PMID 33795634›Full record

ArticleSignal transduction and targeted therapy2021

Small molecule induced polymerization of BCL6 facilitates SIAH1 mediated degradation.

Sandeep Rana, Amarnath Natarajan

Open access · goldAbstract readComment
In one paragraph

Article in Signal transduction and targeted therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Sandeep RanaDivision of Preclinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, MD, USA.
Amarnath NatarajanEppley Institute for Cancer Research, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA. anatarajan@unmc.edu.ORCID 0000-0001-5067-0203
National Institutes of Health · USUniversity of Nebraska Medical Center · US

Funding

PROTACs for pancreatic cancer therapyR21CA251151 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI NATARAJAN, AMARNATH (AMAR) · 2020 to 2020
$393k
U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) CA251151
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Ubiquitin-Protein LigasesPolymerizationProteolysisUbiquitin-Protein Ligases

Identifiers

PMID33795634
PMCPMC8016958
OpenAlexW3149996930

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.