Evidence map›Paper›PMID 33795534›Full record

ArticleMolecules and cells2021

Tsg101 Is Necessary for the Establishment and Maintenance of Mouse Retinal Pigment Epithelial Cell Polarity.

Dai Le, Soyeon Lim, Kwang Wook Min, Joon Woo Park, Youjoung Kim, Taejeong Ha, Kyeong Hwan Moon, Kay-Uwe Wagner, Jin Woo Kim

Open access · diamondAbstract read
In one paragraph

Article in Molecules and cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Dai LeDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.ORCID 0000-0001-6395-6163
Soyeon LimDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.ORCID 0000-0003-3106-2282
Kwang Wook MinDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.ORCID 0000-0002-7593-7047
Joon Woo ParkDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.ORCID 0000-0003-2467-5750
Youjoung KimDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.ORCID 0000-0003-4089-8292
Taejeong HaDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.ORCID 0000-0003-1664-1593
Kyeong Hwan MoonDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.ORCID 0000-0001-9868-2238
Kay-Uwe WagnerDepartment of Oncology, Wayne State University, Detroit, MI 48201, USA.ORCID 0000-0002-5081-0226
Jin Woo KimDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.ORCID 0000-0003-0767-1918
Korea Advanced Institute of Science and Technology · KRWayne State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The retinal pigment epithelium (RPE) forms a monolayer sheet separating the retina and choroid in vertebrate eyes. The polarized nature of RPE is maintained by distributing membrane proteins differentially along apico-basal axis. We found the distributions of these proteins differ in embryonic, post-natal, and mature mouse RPE, suggesting developmental regulation of protein trafficking. Thus, we deleted tumor

Indexed as

AnimalsCell PolarityDNA-Binding ProteinsEndosomal Sorting Complexes Required for TransportEpithelial CellsMembrane ProteinsMiceRetinal Pigment EpitheliumTranscription FactorsTsg101 ProteinDNA-Binding ProteinsEndosomal Sorting Complexes Required for TransportMembrane ProteinsTranscription FactorsTsg101 Proteincell polarityendosomal sorting complexes required for transport (ESCRT)retinal pigment epithelium (RPE)tumor susceptibility gene 101 (Tsg101)

Identifiers

PMID33795534
PMCPMC8019596
OpenAlexW3150079762

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.