Evidence map›Paper›PMID 33795512›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Bacterial-induced pH shifts link individual cell physiology to macroscale collective behavior.

Veeramuthu Dharanishanthi, Amit Orgad, Neta Rotem, Efrat Hagai, Jeny Kerstnus-Banchik, Julius Ben-Ari, Tim Harig, Srinivasa Rao Ravella, Stefan Schulz, Yael Helman

Open access · greenAbstract readVideo-Audio Media
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. pH Sensing Properties of CoSensors (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Veeramuthu DharanishanthiDepartment of Plant Pathology and Microbiology, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, 7610001, Israel.
Amit OrgadDepartment of Plant Pathology and Microbiology, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, 7610001, Israel.
Neta RotemDepartment of Plant Pathology and Microbiology, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, 7610001, Israel.
Efrat HagaiDepartment of Plant Pathology and Microbiology, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, 7610001, Israel.
Jeny Kerstnus-BanchikThe Interdepartmental Unit, Mass Spectrometry and Chromatography Laboratory, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, 7610001, Israel.ORCID 0000-0002-4527-3307
Julius Ben-AriThe Interdepartmental Unit, Mass Spectrometry and Chromatography Laboratory, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, 7610001, Israel.
Tim HarigInstitute of Organic Chemistry, Technische Universität, 38106 Braunschweig, Germany.
Srinivasa Rao RavellaInstitute of Organic Chemistry, Technische Universität, 38106 Braunschweig, Germany.
Stefan SchulzInstitute of Organic Chemistry, Technische Universität, 38106 Braunschweig, Germany.ORCID 0000-0002-4810-324X
Yael HelmanDepartment of Plant Pathology and Microbiology, The Robert H. Smith Faculty of Agriculture, Food and Environment, The Hebrew University of Jerusalem, Rehovot, 7610001, Israel; yael.helman@mail.huji.ac.il.ORCID 0000-0003-0383-2809
Hebrew University of Jerusalem · ILTechnische Universität Braunschweig · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteria have evolved a diverse array of signaling pathways that enable them to quickly respond to environmental changes. Understanding how these pathways reflect environmental conditions and produce an orchestrated response is an ongoing challenge. Herein, we present a role for collective modifications of environmental pH carried out by microbial colonies living on a surface. We show that by collectively adjusting the local pH value,

Indexed as

Bacterial Physiological PhenomenaMicrobial InteractionsFlagellinHydrogen-Ion ConcentrationPaenibacillusProteus mirabilisXanthomonasFlagellincarbon catabolite repressionPaenibacillus spp.pH modulationswarming

Identifiers

PMID33795512
PMCPMC8040824
OpenAlexW3143059704

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.