Evidence map›Paper›PMID 33795496›Full record

ArticleSaudi medical journal2021

Disease phenotype and diagnostic delay in Saudi patients with primary Sjögren's syndrome: An exploratory cross-sectional study.

Mohammed A Omair, Bashaer S AlQahtani, Esam H AlHamad, Yusra A Tashkandy, Nashwa S Othman, Khalid A AlShahrani, Muthurajan P Paramasivam, Fahidah AlEnzi, Rabih Halwani, Maha H Daghestani

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Article in Saudi medical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

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0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Mohammed A OmairFrom the Rheumatology Division (Omair), Pulmonary Division (AlHamad, Paramasivam) Department of Medicine, from the Department of Zoology (AlQahtani, Daghestani), College of Medicine, from the Department of Statistics and Operations Research, College of Sciences (Tashkandy), Central Laboratory (Othman), King Saud University; from the Rheumatology Division, Department of Medicine (AlShahrani), Diriyah General Hospital, Ministry of Health; from the Department of Clinical Science, College of Medicine (AlEnzi), Princess Nourah bint Abdulrahman University, Riyadh, Kingdom of Saudi Arabia; and from the Department of Clinical Sciences, College of Medicine (Halwani), Sharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab Emirates.
Bashaer S AlQahtaniFrom the Rheumatology Division (Omair), Pulmonary Division (AlHamad, Paramasivam) Department of Medicine, from the Department of Zoology (AlQahtani, Daghestani), College of Medicine, from the Department of Statistics and Operations Research, College of Sciences (Tashkandy), Central Laboratory (Othman), King Saud University; from the Rheumatology Division, Department of Medicine (AlShahrani), Diriyah General Hospital, Ministry of Health; from the Department of Clinical Science, College of Medicine (AlEnzi), Princess Nourah bint Abdulrahman University, Riyadh, Kingdom of Saudi Arabia; and from the Department of Clinical Sciences, College of Medicine (Halwani), Sharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab Emirates.
Esam H AlHamadFrom the Rheumatology Division (Omair), Pulmonary Division (AlHamad, Paramasivam) Department of Medicine, from the Department of Zoology (AlQahtani, Daghestani), College of Medicine, from the Department of Statistics and Operations Research, College of Sciences (Tashkandy), Central Laboratory (Othman), King Saud University; from the Rheumatology Division, Department of Medicine (AlShahrani), Diriyah General Hospital, Ministry of Health; from the Department of Clinical Science, College of Medicine (AlEnzi), Princess Nourah bint Abdulrahman University, Riyadh, Kingdom of Saudi Arabia; and from the Department of Clinical Sciences, College of Medicine (Halwani), Sharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab Emirates.
Yusra A TashkandyFrom the Rheumatology Division (Omair), Pulmonary Division (AlHamad, Paramasivam) Department of Medicine, from the Department of Zoology (AlQahtani, Daghestani), College of Medicine, from the Department of Statistics and Operations Research, College of Sciences (Tashkandy), Central Laboratory (Othman), King Saud University; from the Rheumatology Division, Department of Medicine (AlShahrani), Diriyah General Hospital, Ministry of Health; from the Department of Clinical Science, College of Medicine (AlEnzi), Princess Nourah bint Abdulrahman University, Riyadh, Kingdom of Saudi Arabia; and from the Department of Clinical Sciences, College of Medicine (Halwani), Sharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab Emirates.
Nashwa S OthmanFrom the Rheumatology Division (Omair), Pulmonary Division (AlHamad, Paramasivam) Department of Medicine, from the Department of Zoology (AlQahtani, Daghestani), College of Medicine, from the Department of Statistics and Operations Research, College of Sciences (Tashkandy), Central Laboratory (Othman), King Saud University; from the Rheumatology Division, Department of Medicine (AlShahrani), Diriyah General Hospital, Ministry of Health; from the Department of Clinical Science, College of Medicine (AlEnzi), Princess Nourah bint Abdulrahman University, Riyadh, Kingdom of Saudi Arabia; and from the Department of Clinical Sciences, College of Medicine (Halwani), Sharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab Emirates.
Khalid A AlShahraniFrom the Rheumatology Division (Omair), Pulmonary Division (AlHamad, Paramasivam) Department of Medicine, from the Department of Zoology (AlQahtani, Daghestani), College of Medicine, from the Department of Statistics and Operations Research, College of Sciences (Tashkandy), Central Laboratory (Othman), King Saud University; from the Rheumatology Division, Department of Medicine (AlShahrani), Diriyah General Hospital, Ministry of Health; from the Department of Clinical Science, College of Medicine (AlEnzi), Princess Nourah bint Abdulrahman University, Riyadh, Kingdom of Saudi Arabia; and from the Department of Clinical Sciences, College of Medicine (Halwani), Sharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab Emirates.
Muthurajan P ParamasivamFrom the Rheumatology Division (Omair), Pulmonary Division (AlHamad, Paramasivam) Department of Medicine, from the Department of Zoology (AlQahtani, Daghestani), College of Medicine, from the Department of Statistics and Operations Research, College of Sciences (Tashkandy), Central Laboratory (Othman), King Saud University; from the Rheumatology Division, Department of Medicine (AlShahrani), Diriyah General Hospital, Ministry of Health; from the Department of Clinical Science, College of Medicine (AlEnzi), Princess Nourah bint Abdulrahman University, Riyadh, Kingdom of Saudi Arabia; and from the Department of Clinical Sciences, College of Medicine (Halwani), Sharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab Emirates.
Fahidah AlEnziFrom the Rheumatology Division (Omair), Pulmonary Division (AlHamad, Paramasivam) Department of Medicine, from the Department of Zoology (AlQahtani, Daghestani), College of Medicine, from the Department of Statistics and Operations Research, College of Sciences (Tashkandy), Central Laboratory (Othman), King Saud University; from the Rheumatology Division, Department of Medicine (AlShahrani), Diriyah General Hospital, Ministry of Health; from the Department of Clinical Science, College of Medicine (AlEnzi), Princess Nourah bint Abdulrahman University, Riyadh, Kingdom of Saudi Arabia; and from the Department of Clinical Sciences, College of Medicine (Halwani), Sharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab Emirates.
Rabih HalwaniFrom the Rheumatology Division (Omair), Pulmonary Division (AlHamad, Paramasivam) Department of Medicine, from the Department of Zoology (AlQahtani, Daghestani), College of Medicine, from the Department of Statistics and Operations Research, College of Sciences (Tashkandy), Central Laboratory (Othman), King Saud University; from the Rheumatology Division, Department of Medicine (AlShahrani), Diriyah General Hospital, Ministry of Health; from the Department of Clinical Science, College of Medicine (AlEnzi), Princess Nourah bint Abdulrahman University, Riyadh, Kingdom of Saudi Arabia; and from the Department of Clinical Sciences, College of Medicine (Halwani), Sharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab Emirates.
Maha H DaghestaniFrom the Rheumatology Division (Omair), Pulmonary Division (AlHamad, Paramasivam) Department of Medicine, from the Department of Zoology (AlQahtani, Daghestani), College of Medicine, from the Department of Statistics and Operations Research, College of Sciences (Tashkandy), Central Laboratory (Othman), King Saud University; from the Rheumatology Division, Department of Medicine (AlShahrani), Diriyah General Hospital, Ministry of Health; from the Department of Clinical Science, College of Medicine (AlEnzi), Princess Nourah bint Abdulrahman University, Riyadh, Kingdom of Saudi Arabia; and from the Department of Clinical Sciences, College of Medicine (Halwani), Sharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab Emirates.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo describe primary Sjögren's syndrome (pSS) cohort in Saudi Arabiain view in of clinical/serological/histopathological phentotype, and, diagnostic delay.

methodsA cross-sectional study conducted between October 2018 and May 2019. Diagnostic delay was calculated from symptoms onset to clinical diagnosis. The European League Against Rheumatism (EULAR) Sjögren's Syndrome Disease Activity Index (ESSDAI) and EULAR Sjogren's Syndrome Patient Reported Index (ESSPRI) were calculated.

resultsForty-one patients were included in the study. There were predominantly females (78%) with a mean (±SD) age of 58.76±12.7 and disease duration of 4.6±2.28 years. The mean diagnostic delay was 2.2±2.4 (range 1-11) years. Minor salivary gland biopsy was performed on 38 (92.7%) patients with a mean focus score of 2.3± 1.2 points. Interstitial lung disease and arthritis were the most common extra-glandular manifestations (EGM) affecting 27 (65.9%) patients for both. The mean ESSDAI was 9.95±7.73 and ESSPRI was 5.17±2.4.

conclusionSaudi primary Sjogren's syndrome patients have a high prevalence of EGM predominantly arthritis and ILD. The diagnostic delay is variable in our cohort.

Indexed as

Delayed DiagnosisSjogren's SyndromeCross-Sectional StudiesFemaleHumansPhenotypeSaudi ArabiaSeverity of Illness Indexdiagnosisdisease phenotypeprimarySaudiSjögren’s syndrome

Identifiers

PMID33795496
PMCPMC8128627

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