Evidence map›Paper›PMID 33795480›Full record

ArticleRNA (New York, N.Y.)2021

A noncanonical microRNA derived from the snaR-A noncoding RNA targets a metastasis inhibitor.

Daniel Stribling, Yi Lei, Casey M Guardia, Lu Li, Christopher J Fields, Pawel Nowialis, Rene Opavsky, Rolf Renne, Mingyi Xie

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 20 citations in OpenAlex.

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  7. AbioRxiv : the preprint server for biology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Daniel Stribling *Department of Molecular Genetics and Microbiology, University of Florida, Gainesville, Florida 32610, USA.ORCID 0000-0002-0649-9506
Yi Lei *Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, Florida 32610, USA.
Casey M Guardia *Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, Florida 32610, USA.
Lu LiDepartment of Biochemistry and Molecular Biology, University of Florida, Gainesville, Florida 32610, USA.
Christopher J FieldsDepartment of Biochemistry and Molecular Biology, University of Florida, Gainesville, Florida 32610, USA.
Pawel NowialisUF Health Cancer Center, University of Florida, Gainesville, Florida 32610, USA.
Rene OpavskyUF Health Cancer Center, University of Florida, Gainesville, Florida 32610, USA.
Rolf RenneDepartment of Molecular Genetics and Microbiology, University of Florida, Gainesville, Florida 32610, USA.
Mingyi XieUF Genetics Institute, University of Florida, Gainesville, Florida 32610, USA.
University of Florida Health · USUniversity of Florida · US

Funding

"Project 3" MHV68 IncRNA/miRNA interaction in latency and lympomagenesisP01CA214091 · NCI · UNIVERSITY OF FLORIDA · PI Scott A. Tibbetts · 2017 to 2026
$15.9M
RNA metabolism mediated by the Integrator complexR35GM128753 · NIGMS · UNIVERSITY OF FLORIDA · PI MINGYI XIE · 2018 to 2026
$4.0M
The Tumor Suppressor Function of Dnmt3a in Chronic Lymphocytic LeukemiaR01CA188561 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI OPAVSKY, RENE · 2015 to 2019
$1.7M
Noncanonical microRNA biogenesis and function in a gamma herpesvirus and mammalsR00CA190886 · NCI · UNIVERSITY OF FLORIDA · PI XIE, MINGYI · 2016 to 2018
$739k
NCI NIH HHS P01 CA214091NCI NIH HHS R00 CA190886NCI NIH HHS R01 CA188561NIGMS NIH HHS R35 GM128753
6 · The paper itself

Abstract

MicroRNAs (miRNAs) are small noncoding RNAs that function as critical posttranscriptional regulators in various biological processes. While most miRNAs are generated from processing of long primary transcripts via sequential Drosha and Dicer cleavage, some miRNAs that bypass Drosha cleavage can be transcribed as part of another small noncoding RNA. Here, we develop the

Indexed as

3' Untranslated RegionsCell MovementComputational BiologyDEAD-box RNA HelicasesHCT116 CellsHEK293 CellsHumansKaryopherinsMCF-7 CellsMicroRNAsNeoplasmsNM23 Nucleoside Diphosphate KinasesRibonuclease IIIRNA, Long Noncoding3' Untranslated RegionsDEAD-box RNA HelicasesDICER1 protein, humanKaryopherinslong non-coding RNA snaR, humanMicroRNAsNM23 Nucleoside Diphosphate KinasesNME1 protein, humanRibonuclease IIIRNA, Long NoncodingXPO5 protein, humanmicroRNA biogenesisNME1qCLASHribonomicssnaR-A

Identifiers

PMID33795480
PMCPMC8127991
OpenAlexW3150203197

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.