Evidence map›Paper›PMID 33795462›Full record

ArticleCold Spring Harbor protocols2021

Imaging Mitochondrial Dynamics in the

Martin Sihan Feng, Jennifer E Bestman

Open access · greenAbstract read
In one paragraph

Article in Cold Spring Harbor protocols, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Martin Sihan FengDepartment of Biology and Neuroscience Program, William and Mary, Williamsburg, Virginia 23185, USA.
Jennifer E BestmanDepartment of Biology and Neuroscience Program, William and Mary, Williamsburg, Virginia 23185, USA jebestman@wm.edu.
Williams (United States) · US

Funding

Linking mitochondria to experience-dependent cell proliferation in the developing brainR15HD099023 · NICHD · COLLEGE OF WILLIAM AND MARY · PI BESTMAN, JENNIFER E · 2020 to 2020
$319k
NICHD NIH HHS R15 HD099023
6 · The paper itself

Abstract

Notable for producing ATP via oxidative phosphorylation, mitochondria also control calcium homeostasis, lipogenesis, the regulation of reactive oxygen species, and apoptosis. Even within relatively simple cells, mitochondria are heterogeneous with regard to their shape, abundance, movement, and subcellular locations. They exist as interconnected, tubular networks and as motile organelles that are transported along the cytoskeleton for distribution throughout cells. These spatial and morphological features reflect variability in the organelle's capacity to synthesize ATP and support cells. Changes to mitochondria are believed to support cell function and fate, and mitochondrial dysfunction underlies disease in the nervous system. Here we describe an in vivo time-lapse imaging approach to monitor and measure the movement and position of the mitochondria in cells of the developing brain in albino

Indexed as

Mitochondrial DynamicsAnimalsBrainCentral Nervous SystemLarvaMicroscopy, ConfocalMitochondriaNeuronsTime-Lapse ImagingXenopus laevis

Identifiers

PMID33795462
PMCPMC8357028
OpenAlexW3140477973

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.