Evidence map›Paper›PMID 33795317›Full record

ArticleThe European respiratory journal2021

Dietary intake of vitamin A, lung function and incident asthma in childhood.

Mohammad Talaei, David A Hughes, Osama Mahmoud, Pauline M Emmett, Raquel Granell, Stefano Guerra, Seif O Shaheen

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The European respiratory journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

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  14. The Role of Vitamins in the Pathogenesis of Asthma.International journal of molecular sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Mohammad TalaeiInstitute of Population Health Sciences, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK m.talaei@qmul.ac.uk.ORCID 0000-0002-6901-3665
David A HughesMRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.ORCID 0000-0002-9644-8998
Osama MahmoudMRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.ORCID 0000-0003-0342-6704
Pauline M EmmettCentre for Academic Child Health, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.ORCID 0000-0003-1076-4779
Raquel GranellMRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.ORCID 0000-0002-4890-4012
Stefano GuerraAsthma and Airway Disease Research Center, University of Arizona, Tucson, AZ, USA.ORCID 0000-0001-7218-3246
Seif O ShaheenInstitute of Population Health Sciences, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID 0000-0002-7273-8691
University of Bristol · GBQueen Mary University of London · GBUniversity of Arizona · US

Funding

SOUTHWEST ENVIRONMENTAL HEALTH SCIENCES CENTERP30ES006694 · NIEHS · UNIVERSITY OF ARIZONA · PI George S Watts · 1994 to 2026
$36.7M
Medical Research Council G9815508Medical Research Council MC_PC_15018Medical Research Council MC_PC_19009NIEHS NIH HHS P30 ES006694Wellcome TrustWellcome Trust 217065/Z/19/Z
6 · The paper itself

Abstract

backgroundLongitudinal epidemiological data are scarce on the relationship between dietary intake of vitamin A and respiratory outcomes in childhood. We investigated whether a higher intake of preformed vitamin A or pro-vitamin β-carotene in mid-childhood is associated with higher lung function and with asthma risk in adolescence.

methodsIn the Avon Longitudinal Study of Parents and Children, dietary intakes of preformed vitamin A and β-carotene equivalents were estimated by food frequency questionnaire at 7 years of age. Post-bronchodilator forced expiratory volume in 1 s (FEV

resultsIn multivariable adjusted models, a higher intake of preformed vitamin A was associated with higher lung function and a lower risk of incident asthma: comparing top

conclusionA higher intake of preformed vitamin A, but not β-carotene, in mid-childhood is associated with higher subsequent lung function and lower risk of fixed airflow limitation and incident asthma.

Indexed as

AsthmaVitamin AAdolescentbeta-Carotene 15,15'-MonooxygenaseChildEatingForced Expiratory VolumeHumansLongitudinal StudiesLungVital CapacityBCO1 protein, humanbeta-Carotene 15,15'-MonooxygenaseVitamin A

Identifiers

PMID33795317
PMCPMC8551559
OpenAlexW3142960846

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.