Evidence map›Paper›PMID 33795273›Full record

ArticleBMJ case reports2021

Unintentional ingestion of a high dose of acenocoumarol in a young child.

Martijn R Brands, Jelmer Sytema, Marinus van Hulst, Arvid Wa Kamps

Open access · hybridAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Martijn R Brands *Paediatrics, Martini Hospital, Groningen, The Netherlands.ORCID http://orcid.org/0000-0002-3188-5900
Jelmer Sytema *Clinical Pharmacy and Toxicology, Martini Hospital, Groningen, The Netherlands.ORCID http://orcid.org/0000-0002-7288-156X
Marinus van HulstClinical Pharmacy and Toxicology, Martini Hospital, Groningen, The Netherlands m.van.hulst@rug.nl.ORCID http://orcid.org/0000-0003-3216-7246
Arvid Wa KampsPaediatrics, Martini Hospital, Groningen, The Netherlands.ORCID http://orcid.org/0000-0002-3533-2676
Martini Ziekenhuis · NLUniversity Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute intoxication with a vitamin K antagonist may cause serious coagulopathy. We report the accidental ingestion of a high dose of acenocoumarol in a young child. Two intravenous administrations of 5 mg of vitamin K, in combination with fast and repeated administration of activated charcoal and sodium sulfate, were sufficient to prevent coagulopathy and related symptoms, despite a confirmed elevated blood acenocoumarol concentration (260 µg/L).

Indexed as

AcenocoumarolBlood Coagulation DisordersAnticoagulantsChildEatingHumansVitamin KAcenocoumarolAnticoagulantsVitamin Khaematology (drugs and medicines)haematology (incl blood transfusion)paediatrics (drugs and medicines)poisoningwarfarin therapy

Identifiers

PMID33795273
PMCPMC8023619
OpenAlexW3144307363

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.