Evidence map›Paper›PMID 33795238›Full record

ReviewDevelopment (Cambridge, England)2021

Diversity and robustness of bone morphogenetic protein pattern formation.

Aasakiran Madamanchi, Mary C Mullins, David M Umulis

Abstract readReview
In one paragraph

Review in Development (Cambridge, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. BMP signaling pathway member expression is enriched in enteric neural progenitors and required for zebrafish enteric nervous system development.Developmental dynamics : an official publication of the American Association of Anatomists · 2025
    Article
  9. Article
  10. Morphogens in the evolution of size, shape and patterning.Development (Cambridge, England) · 2024
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. How two extraembryonic epithelia became one: serosa and amnion features and functions ofPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022
    Review
  16. Bmp4 Synexpression Gene,International journal of molecular sciences · 2022
    Article
  17. Article
  18. Article
  19. Article
  20. BMP Signaling: Lighting up the Way for Embryonic Dorsoventral Patterning.Frontiers in cell and developmental biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aasakiran MadamanchiAgricultural and Biological Engineering. Purdue University, West Lafayette, IN 47907, USA.ORCID 0000-0003-1047-6646
Mary C MullinsDepartment of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA mullins@pennmedicine.upenn.edu dumulis@purdue.edu.
David M UmulisAgricultural and Biological Engineering. Purdue University, West Lafayette, IN 47907, USA mullins@pennmedicine.upenn.edu dumulis@purdue.edu.ORCID 0000-0003-1913-2284

Funding

Oocyte polarity and BMP-mediated dorsoventral patterningR35GM131908 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI Mary C. Mullins · 2019 to 2026
$5.6M
Modeling and analysis of BMP-mediated Dorsal/Ventral patterning in zebrafish embryosR01GM132501 · NIGMS · PURDUE UNIVERSITY · PI UMULIS, DAVID MICHAEL · 2019 to 2022
$1.4M
NIGMS NIH HHS R01 GM132501NIGMS NIH HHS R35 GM131908
6 · The paper itself

Abstract

Pattern formation by bone morphogenetic proteins (BMPs) demonstrates remarkable plasticity and utility in several contexts, such as early embryonic development, tissue patterning and the maintenance of stem cell niches. BMPs pattern tissues over many temporal and spatial scales: BMP gradients as short as 1-2 cell diameters maintain the stem cell niche of the

Indexed as

Bone DevelopmentEmbryonic DevelopmentAnimalsBody PatterningBone and BonesBone Morphogenetic ProteinsDrosophilaDrosophila melanogasterDrosophila ProteinsEmbryo, NonmammalianGene Expression Regulation, DevelopmentalSignal TransductionXenopus laevisZebrafishZebrafish ProteinsBone Morphogenetic ProteinsDrosophila ProteinsZebrafish ProteinsAxis formationBMP patterningDrosophilaMorphogen gradientZebrafish

Identifiers

PMID33795238
PMCPMC8034876

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.