ArticleBMC palliative care2021
Comparison of the health-related quality of life of end stage kidney disease patients on hemodialysis and non-hemodialysis management in Uganda.
Article in BMC palliative care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
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Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Quality-of-life measures and their psychometric properties used in African chronic kidney disease populations: a systematic review using COSMIN methodology.BMC nephrology · 2024Pooled it
- The life quality of people living with chronic disease in Africa: a systematic narrative synthesis.The Pan African medical journal · 2024Pooled it
- Quality of Life of Patients with End-stage Renal Disease Undergoing Hemodialysis in Morocco: Cross-sectional Study.Annals of African medicine · 2026Article
- Psychological Distress, Stress, and Personality Traits in Patients Undergoing Chronic Hemodialysis: A Comparative Psychometric Study.Behavioral sciences (Basel, Switzerland) · 2026Article
- Single-center cross-sectional study of outcomes in hemodialysis patients in Niger: experience from the hemodialysis center at Zinder National Hospital.BMC nephrology · 2026Article
- Severity of restless leg syndrome in patients undergoing hemodialysis: assessing its burden on quality of life and knowledge.Frontiers in nephrology · 2026Article
- Malaria associated pathogenesis of chronic kidney disease (MAP-CKD): a prospective study of children hospitalized with severe malaria.BMC nephrology · 2025Article
- Quality of life and social reinsertion of patients on maintenance haemodialysis in four government funded hospitals in Cameroon.BMC nephrology · 2024Article
- Health related quality of life of patients undergoing in-centre hemodialysis in Rwanda: a cross sectional study.BMC nephrology · 2022Article
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8 authors.
Funding
Abstract
backgroundHealth-related quality of life is recognized as a key outcome in chronic disease management, including kidney disease. With no national healthcare coverage for hemodialysis, Ugandan patients struggle to pay for their care, driving families and communities into poverty. Studies in developed countries show that patients on hemodialysis may prioritize quality of life over survival time, but there is a dearth of information on this in developing countries. We therefore measured the quality of life (QOL) and associated factors in end stage renal disease (ESRD) patients in a major tertiary care hospital in Uganda.
methodsBaseline QOL measurement in a longitudinal cohort study was undertaken using the Kidney Disease Quality of Life Short Form Ver 1.3. Patients were recruited from the adult nephrology unit if aged > 18 years with an estimated glomerular filtration rate ≤ 15mls/min/1,73m
resultsThree hundred sixty-four patients (364) were recruited, of whom 124 were on hemodialysis (HD) and 240 on non-hemodialysis (non-HD) management. Overall, 94.3% of participants scored less than 50 (maximum 100). Mean QOL scores were low across all three principal domains: physical health (HD: 33.14, non-HD: 34.23), mental health (HD: 38.01, non-HD: 38.02), and kidney disease (HD: 35.16, non-HD: 34.00). No statistically significant difference was found between the overall quality of life scores of the two management groups. Breadwinner status (p < 0.001), source of income (p0.026) and hemodialysis management type (p0.032) were the only factors significantly associated with QOL scores, and this was observed in the physical health and kidney disease principal domains only. No factors were significantly associated with scores for the mental health principal domain and/or overall QOL score.
conclusionThe quality of life of Ugandan patients with ESRD has been found to be lower across all three domains of the Kidney Disease Quality of Life Short Form than reported anywhere in the world, with no difference observed between the non-HD and HD management groups. Interventions targeting all domains of QOL are needed among patients with ESRD in Uganda and, potentially, in other resource limited settings.
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