ArticleBMC infectious diseases2021
C-reactive protein predicts complications in community-associated S. aureus bacteraemia: a cohort study.
Article in BMC infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed.
- Genetic determinants of Staphylococcus aureus adhesion shape virulence trade-offs in bacteremia.Nature communications · 2026Article
- Impact of sex on clinical management and mortality in community-onset Staphylococcus aureus bacteraemia: a retrospective study.BMC infectious diseases · 2026Article
- Clinical and laboratory predictors of mortality inAnnals of medicine · 2025Observational
- Predictors of mortality inThe Journal of international medical research · 2025Observational
- Community-acquired Staphylococcus aureus bacteremia in healthy children-13 years of experience in a pediatric tertiary center.European journal of pediatrics · 2025Article
- Risk Factors for Persistent Staphylococcus aureus Bacteremia in Children.The Pediatric infectious disease journal · 2024Observational
- Phenome-wide association study identifies new clinical phenotypes associated with Staphylococcus aureus infections.PloS one · 2024Article
- Predictors of infectious foci on FDG PET/CT in Staphylococcus aureus bacteremia.Scientific reports · 2023Article
- Risk Factors of Coexisting Septic Spondylitis and Arthritis: A Case-Control Study in a Tertiary Referral Hospital.Journal of clinical medicine · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStaphylococcus aureus (S. aureus) bacteraemia is increasingly acquired from community settings and is associated with a mortality rate of up to 40% following complications. Identifying risk factors for complicated S. aureus bacteraemia would aid clinicians in targeting patients that benefit from expedited investigations and escalated care.
methodsIn this prospective observational cohort study, we aimed to identify risk factors associated with a complicated infection in community-onset S. aureus bacteraemia. Potential risk factors were collected from electronic medical records and included: - patient demographics, symptomology, portal of entry, and laboratory results.
resultsWe identified several potential risk factors using univariate analysis. In a multiple logistic regression model, age, haemodialysis, and entry point from a diabetic foot ulcer were all significantly protective against complications. Conversely, an unknown entry point of infection, an entry point from an indwelling medical device, and a C-reactive protein concentration of over 161 mg/L on the day of admission were all significantly associated with complications.
conclusionsWe conclude that several factors are associated with complications including already conducted laboratory investigations and portal of entry of infection. These factors could aid the triage of at-risk patients for complications of S. aureus bacteraemia.
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