Evidence map›Paper›PMID 33794726›Full record

ArticleAutophagy2021

ATG14 and RB1CC1 play essential roles in maintaining muscle homeostasis.

Dongfang Li, Peter Vogel, Xiujie Li-Harms, Bo Wang, Mondira Kundu

Open access · bronzeAbstract read
In one paragraph

Article in Autophagy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 11 citations in OpenAlex.

  1. The ATG14: multi-layer autophagy control and an emerging therapeutic target in cancer.Apoptosis : an international journal on programmed cell death · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Physiological functions of ULK1/2.Journal of molecular biology · 2024
    Review
  9. Article
  10. Autophagy in striated muscle diseases.Frontiers in cardiovascular medicine · 2022
    Review
  11. Managing risky assets - mitophagy in vivo.Journal of cell science · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Dongfang LiDepartments of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Peter VogelDepartments of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Xiujie Li-HarmsDepartments of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Bo WangDepartments of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Mondira KunduDepartments of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
St. Jude Children's Research Hospital · US

Funding

Role of the autophagy-inducing kinases ULK1/2 in ER export and protein traffickingR01MH115058 · NIMH · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI KUNDU, MONDIRA · 2018 to 2022
$2.2M
Mechanisms of Mitochondrial Degradation in Unstressed Mammalian CellsR01GM132231 · NIGMS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI KUNDU, MONDIRA · 2020 to 2022
$1.1M
NIGMS NIH HHS R01 GM132231NIMH NIH HHS R01 MH115058
6 · The paper itself

Abstract

Defects in macroautophagy/autophagy are implicated in the pathogenesis of neuromuscular and heart diseases. To precisely define the roles of autophagy-related genes in skeletal and cardiac muscles, we generated muscle-specific

Indexed as

AutophagyMusclesAnimalsAutophagy-Related Protein-1 HomologAutophagy-Related ProteinsHomeostasisMiceVesicular Transport ProteinsAtg14 protein, mouseAutophagy-Related Protein-1 HomologAutophagy-Related ProteinsRb1cc1 protein, mouseVesicular Transport ProteinsATG14autophagic vacuolar myopathyautophagycardiomyopathyinclusion body myopathyRB1CC1RNA-binding proteinULK1ULK2

Identifiers

PMID33794726
PMCPMC8496527
OpenAlexW3150928251

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.