Evidence map›Paper›PMID 33793888›Full record

ReviewPlant physiology2021

Contemporary proteomic strategies for cysteine redoxome profiling.

Patrick Willems, Frank Van Breusegem, Jingjing Huang

Abstract readReview
In one paragraph

Review in Plant physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. The ascorbate-glutathione cycle coming of age.Journal of experimental botany · 2024
    Review
  4. Review
  5. Review
  6. Plant redox biology-on the move.Plant physiology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Patrick WillemsDepartment of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium.ORCID 0000-0003-4667-2294
Frank Van BreusegemDepartment of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium.ORCID 0000-0002-3147-0860
Jingjing HuangDepartment of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium.ORCID 0000-0002-4963-3162

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein cysteine residues are susceptible to oxidative modifications that can affect protein functions. Proteomic techniques that comprehensively profile the cysteine redoxome, the repertoire of oxidized cysteine residues, are pivotal towards a better understanding of the protein redox signaling. Recent technical advances in chemical tools and redox proteomic strategies have greatly improved selectivity, in vivo applicability, and quantification of the cysteine redoxome. Despite this substantial progress, still many challenges remain. Here, we provide an update on the recent advances in proteomic strategies for cysteine redoxome profiling, compare the advantages and disadvantages of current methods and discuss the outstanding challenges and future perspectives for plant redoxome research.

Indexed as

MetabolomeOxidation-ReductionCysteinePlant ProteinsPlantsProteomeProteomicsCysteinePlant ProteinsProteome

Identifiers

PMID33793888
PMCPMC8154054

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.