SynthesisPloS one2021
Are neuromuscular adaptations present in people with recurrent spinal pain during a period of remission? a systematic review.
Synthesis in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- The effects of ageing on fatigue and endurance of the spinal extensor muscles: a systematic review and meta-analysis.GeroScience · 2026Pooled it
- Physical and Psychological Predictors for Persistent and Recurrent Non-Specific Neck Pain: A Systematic Review.European journal of pain (London, England) · 2025Pooled it
- Does pain influence control of muscle force? A systematic review and meta-analysis.European journal of pain (London, England) · 2025Pooled it
- Convergent validity of the position-reposition and thoracolumbar dissociation tests in patients with recurrent low back pain in remission.Brazilian journal of physical therapy · 2026Article
- Altered transversus abdominis and internal oblique muscle activation during cervical motor control tasks in individuals with chronic neck pain: A surface EMG-based analysis.Journal of back and musculoskeletal rehabilitation · 2026Article
- Machine learning identifies distinct movement control impairment clusters in patients with chronic neck pain.Scientific reports · 2026Article
- Article
- Development and Validation of a Nomogram for Predicting Recurrence in Patients Previously Treated Conservatively for Cervical Spondylosis.International journal of general medicine · 2026Article
- Task-specific pain-related fear influences lifting biomechanics differently in individuals with and without occupations involving repetitive lifting tasks.Scientific reports · 2025Article
- Direction Matters: A Crossover Study on Motor Adaptations to Movement-Evoked Pain Induced in the Lumbar Region.European journal of pain (London, England) · 2025Article
- Altered proprioceptive weighting and trunk muscle activation in individuals with recurrent low back pain: a cross-sectional study.BMC musculoskeletal disorders · 2025Article
- Validity and Reliability of the Turkish Version of the Sensory-Motor Dysfunction Questionnaire.Brain and behavior · 2025Article
- Neck Pain in Dental Education: A Cross-Sectional Analysis of Neck Strength Differences.Muscles (Basel, Switzerland) · 2025Article
- Trunk Laterality Judgement in Chronic Low Back Pain: Influence of Low Back Pain History, Task Complexity, and Clinical Correlates.Journal of clinical medicine · 2025Article
- A novel protocol to investigate the monoaminergic relationship between descending nociceptive and motor unit neuromodulation.Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2025Article
- Motion analysis of 3D multi-segmental spine during gait in symptom remission people with low back pain: a pilot study.BMC musculoskeletal disorders · 2025Article
- Article
- Article
- Reliability of the Second and Third Iterations of the Sensory-Motor Dysfunction Questionnaire in a Subclinical Neck Pain Population.Brain sciences · 2025Article
- Known-Group Validity and Sensitivity to Change in the Sensory-Motor Dysfunction Questionnaire in Individuals with Neck Pain: A Pilot Study.Brain sciences · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A plethora of evidence supports the existence of neuromuscular changes in people with chronic spinal pain (neck and low back pain), yet it is unclear whether neuromuscular adaptations persist for people with recurrent spinal pain when in a period of remission. This systematic review aimed to synthesise the evidence on neuromuscular adaptations in people with recurrent spinal pain during a period of remission. Electronic databases, grey literature, and key journals were searched from inception up to the 4th of September 2020. Eligibility criteria included observational studies investigating muscle activity, spine kinematics, muscle properties, sensorimotor control, and neuromuscular performance in adults (≥ 18 years) with recurrent spinal pain during a period of remission. Screening, data extraction, and quality assessment (Newcastle-Ottawa Scale) were conducted independently by two reviewers. Data synthesis was conducted per outcome domain. A meta-analysis with a random-effects model was performed where possible. The overall strength of evidence was rated using the Grading of Recommendations, Assessment, Development and Evaluation guidelines (GRADE). From 8292 records, 27 and five studies were included in a qualitative and quantitative synthesis, respectively. Very low level of evidence supports muscle activity changes in people with recurrent low back pain, especially greater co-contraction, redistribution of muscle activity, and delayed postural control of deeper trunk muscles. Reduced range of motion of the lumbar spine was also found. Meaningful conclusions regarding other outcome domains or people with recurrent neck pain could not be drawn. In conclusion, people with recurrent low back pain during a period of remission show muscle activity and spine kinematics adaptations. Future research should investigate the long-term impact of these changes, as well as adaptations in people with recurrent neck pain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.