Evidence map›Paper›PMID 33793090›Full record

ArticleACR open rheumatology2021

Geographic Variation in the Prevalence of Rheumatoid Arthritis in Alberta, Canada.

Xiaoxiao Liu, Claire E H Barber, Steven Katz, Joanne Homik, Stefania Bertazzon, Alka B Patel, Jill Robert, Christopher Smith, Dianne Mosher, Deborah A Marshall

Abstract read
In one paragraph

Article in ACR open rheumatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiaoxiao LiuUniversity of Calgary, Calgary, Alberta, Canada.ORCID https://orcid.org/0000-0003-2479-897X
Claire E H BarberUniversity of Calgary, Calgary, Alberta, Canada, and Arthritis Research Canada, Richmond, British Columbia, Canada.ORCID https://orcid.org/0000-0002-3062-5488
Steven KatzUniversity of Alberta, Edmonton, Alberta, Canada.
Joanne HomikUniversity of Alberta, Edmonton, Alberta, Canada.
Stefania BertazzonUniversity of Calgary, Calgary, Alberta, Canada.
Alka B PatelUniversity of Calgary, Calgary, Alberta, Canada, and Alberta Health Services, Edmonton, Alberta, Canada.
Jill RobertAlberta Health Services, Edmonton, Alberta, Canada.
Christopher SmithAlberta Bone and Joint Health Institute, Calgary, Alberta, Canada.
Dianne MosherUniversity of Calgary, Calgary, Alberta, Canada.
Deborah A MarshallUniversity of Calgary, Calgary, Alberta, Canada, and Arthritis Research Canada, Richmond, British Columbia, Canada.ORCID https://orcid.org/0000-0002-8467-8008

Funding

Arthur J.E. Child Chair in Rheumatology ResearchCanadian Initiative for Outcomes in Rheumatology Care grant competition (CIORA)Cumming School of Medicine Postdoctoral ScholarshipMcCaig Institute for Bone and Joint Health Postdoctoral ScholarshipO'Brien Institute of Public Health Postdoctoral Scholarship
6 · The paper itself

Abstract

objectivesTimely access to rheumatologists remains a challenge in Alberta, a Canadian province with vast rural areas, whereas rheumatologists are primarily clustered in metro areas. To address the goal of timely and equitable access to rheumatoid arthritis (RA) care, health planners require information at the regional and local level to determine the RA prevalence and the associated health care needs.

methodsUsing Alberta Health administrative databases, we identified RA-prevalent cases (April 1, 2015-March 31, 2016) on the basis of a validated case definition. Age- and sex-standardized prevalence rates per 1000 population members and the standardized rates ratio (SRR) were calculated. We applied Global Moran's I and Gi* hotspot analysis using three different weight matrices to explore the geospatial pattern of RA prevalence in Alberta.

resultsAmong 38 350 RA cases (68% female; n = 26 236), the prevalence rate was 11.81 cases per 1000 population members (95% confidence interval [CI] 11.80-11.81) after age and sex standardization. Approximately 60% of RA cases resided in metro (Calgary and Edmonton) and moderate metro areas. The highest rate was observed in rural areas (14.46; 95% CI 14.45-14.47; SRR 1.28), compared with the lowest in metro areas (10.69; 95% CI 10.68-10.69; SRR 0.82). The RA prevalence across local geographic areas ranged from 4.7 to 30.6 cases. The Global Moran's I index was 0.15 using three different matrices (z-score 3.96-4.24). We identified 10 hotspots in the south and north rural areas and 18 cold spots in metro and moderate metro Calgary.

conclusionThe findings highlight notable rural-urban variation in RA prevalence in Alberta. Our findings can inform strategies aimed at reducing geographic disparities by targeting areas with high health care needs.

Identifiers

PMID33793090
PMCPMC8126758

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.