Evidence map›Paper›PMID 33792823›Full record

ArticleTechniques in coloproctology2021

T2-weighted, apparent diffusion coefficient and

F Crimì, R Stramare, G Spolverato, V Aldegheri, A Barison, L D'Alimonte, Q R Bao, A Spimpolo, L Albertoni, D Cecchin and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Techniques in coloproctology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

F CrimìInstitute of Radiology, Department of Medicine (DIMED), University Hospital of Padova, Padova, Italy.
R StramareInstitute of Radiology, Department of Medicine (DIMED), University Hospital of Padova, Padova, Italy.
G SpolveratoClinica Chirurgica I, Department of Surgical, Oncological and Gastroenterological Sciences (DiSCOG), University Hospital of Padova, Via Nicolò Giustiniani 2, 35128, Padova, Italy. gaya.spolverato@unipd.it.ORCID http://orcid.org/0000-0002-7275-2573
V AldegheriInstitute of Radiology, Department of Medicine (DIMED), University Hospital of Padova, Padova, Italy.
A BarisonInstitute of Radiology, Department of Medicine (DIMED), University Hospital of Padova, Padova, Italy.
L D'AlimonteClinica Chirurgica I, Department of Surgical, Oncological and Gastroenterological Sciences (DiSCOG), University Hospital of Padova, Via Nicolò Giustiniani 2, 35128, Padova, Italy.
Q R BaoClinica Chirurgica I, Department of Surgical, Oncological and Gastroenterological Sciences (DiSCOG), University Hospital of Padova, Via Nicolò Giustiniani 2, 35128, Padova, Italy.ORCID http://orcid.org/0000-0003-3463-6659
A SpimpoloNuclear Medicine Unit, Department of Medicine (DIMED), University Hospital of Padova, Padova, Italy.
L AlbertoniSurgical Pathology and Cytopathology Unit, Department of Medicine (DIMED), University Hospital of Padova, Padova, Italy.
D CecchinNuclear Medicine Unit, Department of Medicine (DIMED), University Hospital of Padova, Padova, Italy.
C CampiDepartment of Mathematics "Tullio Levi-Civita", University of Padova, Padova, Italy.
E QuaiaInstitute of Radiology, Department of Medicine (DIMED), University Hospital of Padova, Padova, Italy.
S PucciarelliClinica Chirurgica I, Department of Surgical, Oncological and Gastroenterological Sciences (DiSCOG), University Hospital of Padova, Via Nicolò Giustiniani 2, 35128, Padova, Italy.
P ZucchettaNuclear Medicine Unit, Department of Medicine (DIMED), University Hospital of Padova, Padova, Italy.
University of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of our study was to investigate the correlation among T2-weighted (T2w) images, apparent diffusion coefficient (ADC) maps,

methodsPatients with LARC were prospectively enrolled between February 2015 and August 2018 and underwent PET/magnetic resonance imaging (MRI). MRI included T2w and diffusion-weighted imaging (DWI)-sequences. ADC maps and PET images were matched to the T2w images. Voxel-based standardized uptake values (SUVs,) ADC and T2w-signal-intensity values were collected from the volumes of interest (VOIs) and mean, skewness and kurtosis were calculated. Spearman's correlation coefficient was applied to evaluate the correlation among the variables and tumor regression grade (TRG), T stage, N stage and fibrosis.

resultsTwenty-two patients with biopsy-proven LARC in the low or mid rectum were enrolled [17 males, mean age was 69 years (range 49-85 years)]. Seven patients experienced complete regression (TRG1). A significant positive correlation was found between SUV mean values (ρ = 0.480; p = 0.037) and TRG. No other significant correlations were found.

conclusionsHistogram analysis of SUV values is a predictor of TRG in LARC.

Indexed as

Fluorodeoxyglucose F18Rectal NeoplasmsAgedAged, 80 and overChemoradiotherapyDiffusion Magnetic Resonance ImagingHumansMaleMiddle AgedNeoadjuvant TherapyPositron-Emission TomographyFluorodeoxyglucose F18Magnetic resonance imaging (MRI)Positron emission tomography (PET)Preoperative chemoradiotherapyRectal cancer

Identifiers

PMID33792823
PMCPMC8079287
OpenAlexW3149152434

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.