ArticleEnvironmental science and pollution research international2021
The effects of bisphenol A given in ovo on bursa of Fabricius development and percentage of acid phosphatase positive lymphocyte in chicken.
Article in Environmental science and pollution research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 11 citations in OpenAlex.
- Evaluating dried pomegranate peel as a functional feed additive: effects on growth, carcass traits, and gut health in broilers.Tropical animal health and production · 2025Article
- Determination of the embryotoxic effects of propofol injected into eggs on the cerebellum and spinal cord using histologic methods: an animal study.Turkish journal of medical sciences · 2024Article
- Modulation of Immunity, Antioxidant Status, Performance, Blood Hematology, and Intestinal Histomorphometry in Response to Dietary Inclusion ofLife (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Bisphenol A (BPA), one of the endocrine disrupting chemicals, is the object of great concern because of its widespread use throughout the world. In this study, it was aimed to determine the effects of in ovo administrated BPA on the bursa of Fabricius and percentage of acid phosphatase positive lymphocyte in peripheral blood by means of histological and enzyme histochemical methods. For this purpose, 310 fertile eggs of Isa Brown laying parent stock were used. The eggs were divided into 5 groups as control, vehicle control, 50, 100, and 250μg/egg BPA. At days 13, 18, and 21 of incubation, eggs were opened until 10 living embryos were obtained from each group. Tissue samples were taken from the obtained embryos and processed for enzyme histochemical methods in addition to routine histological techniques. It was observed that, in BPA-treated groups, embryonic development of bursa of Fabricius was retarded. It was also indicated that the percentage of peripheral blood ACP-ase positive lymphocytes was significantly decreased. These results suggested that a limited maternal transfer of BPA into the eggs might be lead to immunosuppression in chicks.
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Registered trials
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