Evidence map›Paper›PMID 33791885›Full record

Observational studyGastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association2021

QOL assessment after palliative surgery for malignant bowel obstruction caused by peritoneal dissemination of gastric cancer: a prospective multicenter observational study.

Yuichi Ito, Kazumasa Fujitani, Kentaro Sakamaki, Masahiko Ando, Ryohei Kawabata, Yutaka Tanizawa, Takaki Yoshikawa, Takanobu Yamada, Motohiro Hirao, Makoto Yamada and 7 more

Open access · bronzeAbstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 4 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 4 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Guideline
  2. Health utility book: A systematic review and meta-analysis of health utilities in gastric cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Revisiting malignant gastric outlet obstruction: Where do we stand?World journal of gastrointestinal endoscopy · 2025
    Article
  8. Article
  9. Article
  10. Survival analysis of a prospective multicenter observational study on surgical palliation among patients with malignant bowel obstruction caused by peritoneal dissemination of gastric cancer.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2022
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 15 institutions in 1 country.

Yuichi ItoDepartment of Gastroenterological Surgery, Aichi Cancer Center Hospital, 1-1, Kanokoden, Chikusa-ku, Nagoya, Aichi, 464-8681, Japan. yuichi@aichi-cc.jp.ORCID 0000-0003-4692-3110
Kazumasa FujitaniDepartment of Surgery, Osaka Prefectural General Medical Center, Osaka, Japan.
Kentaro SakamakiCenter for Data Science, Yokohama City University, Yokohama, Japan.
Masahiko AndoCenter for Advanced Medicine and Clinical Research, Nagoya University Hospital, Nagoya, Japan.
Ryohei KawabataDepartment of Surgery, Osaka Rosai Hospital, Sakai, Japan.
Yutaka TanizawaDivision of Gastric Surgery, Shizuoka Cancer Center, Shizuoka, Japan.
Takaki YoshikawaDepartment of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan.
Takanobu YamadaDepartment of Gastrointestinal Surgery, Kanagawa Cancer Center, Yokohama, Japan.
Motohiro HiraoDepartment of Surgery, National Hospital Organization, Osaka National Hospital, Osaka, Japan.
Makoto YamadaDepartment of Surgery, Gifu Municipal Hospital, Gifu, Japan.
Jun HiharaDepartment of Surgery, Hiroshima City Asa Hospital, Hiroshima, Japan.
Ryoji FukushimaDepartment of Surgery, Teikyo University School of Medicine, Tokyo, Japan.
Yasuhiro ChodaDepartment of Surgery, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan.
Yasuhiro KoderaDepartment of Gastroenterological Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Shin TeshimaDepartment of Surgery, National Hospital Organization Sendai Medical Center, Sendai, Japan.
Hisashi ShinoharaDepartment of Surgery, Hyogo College of Medicine, Nishinomiya, Japan.
Masato KondoDepartment of Surgery, Kobe City Medical Center General Hospital, Kobe, Japan.
Hiroshima City Asa Citizens Hospital · JPKanagawa Prefectural Hospital Organization · JPAichi Cancer Center · JPGifu Municipal Hospital · JPHyogo Medical University · JPKobe City Medical Center General Hospital · JPNagoya University · JPNagoya University Hospital · JPOsaka National Hospital · JPOsaka Prefectural Medical Center · JPOsaka Rosai Hospital · JPSendai Medical Center · JPShizuoka Cancer Center · JPTeikyo University · JPYokohama City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with peritoneal dissemination of gastric cancer have poor oral intake caused by malignant bowel obstruction (MBO). Palliative surgery has often been undertaken to improve quality of life (QOL), but few prospective studies on palliative surgery in this patient population have been published. PATIENTS AND

methodsWe prospectively investigated the significance of palliative surgery using patient-reported QOL measures. Patients underwent palliative surgery by small intestine/colon resection or small intestine/colon bypass or ileostomy/colostomy for MBO. The primary endpoint was change in QOL assessed at baseline, 14 days, 1 month, and 3 months following palliative surgery using the Euro QoL Five Dimensions (EQ-5D™) questionnaire and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire gastric cancer module (QLQ-STO22). Secondary endpoints were postoperative improvement in oral intake and surgical complications.

resultsBetween April 2013 and March 2018, 63 patients were enrolled from 14 institutions. The mean EQ-5D™ utility index baseline score of 0.6 remained consistent. Gastric-specific symptoms mostly showed statistically significant improvement from baseline. Forty-two patients (67%) were able to eat solid food 2 weeks after palliative surgery and 36 patients (57%) tolerated it for 3 months. The rate of overall morbidity of ≥ grade III according to the Clavien-Dindo classification was 16% (10 patients) and the 30-day postoperative mortality rate was 3.2% (2 patients).

conclusionsIn patients with MBO caused by peritoneal dissemination of gastric cancer, palliative surgery did not improve QOL while improving solid food intake, with an acceptable postoperative morbidity and mortality rate.

Indexed as

Quality of LifeStomach NeoplasmsHumansPalliative CareProspective StudiesRetrospective StudiesGastric cancerMalignant bowel obstructionPalliative surgeryPeritoneal disseminationProspective multicenter observational studyQuality of life

Identifiers

PMID33791885
OpenAlexW3140243740

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.