SynthesisEuropean radiology2021
Diagnostic procedures and clinico-radiological findings of acute fibrinous and organizing pneumonia: a systematic review and pooled analysis.
Synthesis in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical characteristics and prognostic factors of Hermansky-Pudlak syndrome with or without pulmonary fibrosis: a systematic review.Therapeutic advances in respiratory diseasePooled it
- Acute Fibrinous and Organizing Pneumonia Versus Organizing Pneumonia: A Comparative Study of Clinical, Radiological, Histological, and Immunophenotypic Features.Journal of clinical medicine · 2026Article
- A Mimic of Metastatic Malignancy: Dietary Supplement-Associated Drug-Induced Lung Injury Presenting as Multiple Pulmonary Nodules With an Acute Fibrinous and Organizing Pneumonia Pattern.Respirology case reports · 2026Article
- Korean Guidelines for Diagnosis and Management of Interstitial Lung Disease: Cryptogenic Organizing Pneumonia.Tuberculosis and respiratory diseases · 2025Article
- Clinicopathologic Features of Isolated AFOP Nodules Radiologically Mimicking Malignancy in Post COVID-19 Patients: A Case Series Study.Journal of clinical medicine · 2025Article
- Acute fibrinous and organizing pneumonia after lung transplantation: A case report of treatment with infliximab and tocilizumab and literature review.Respiratory medicine case reports · 2025Article
- Rare interstitial lung diseases: a narrative review.Journal of thoracic disease · 2024Review
- Acute fibrinous and organizing pneumonia associated with Candida: A case report.Respiratory medicine case reports · 2024Article
- Review
- Lesson of urgent bilateral lobar lung transplantation for acute fibrinous and organizing pneumonia: a case report.AME case reports · 2023Article
- Update on cryptogenic organizing pneumonia.Frontiers in medicine · 2023Review
- Case report: Corticosteroid-resistant acute fibrinous and organizing pneumonia with myelodysplastic syndrome.Frontiers in medicine · 2022Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the clinico-radiological findings of acute fibrinous and organizing pneumonia (AFOP) in the literature according to whether a surgical or non-surgical biopsy was performed, as well as to identify prognostic predictors.
methodsWe searched the Embase and OVID-MEDLINE databases to identify studies that presented CT findings of AFOP and had extractable individual patient data. We compared the clinical and CT findings of the patients depending on whether a surgical or non-surgical biopsy was performed and identified survival predictors using a multivariate logistic regression analysis.
resultsEighty-one patients (surgical biopsy, n = 52; non-surgical biopsy, n = 29) from 63 studies were included. The surgical biopsy group frequently experienced an acute fulminant presentation (p = .011) and dyspnea (p = .001) and less frequently had a fever (p = .006) than the non-surgical biopsy group. The surgical biopsy group had a worse prognosis than the non-surgical biopsy group in terms of mechanical ventilation and mortality (both, p = .023). For survival analysis, the patients with the predominant CT finding of patchy or mass-like air-space consolidation survived more frequently (p < .001) than those with other CT findings. For prognostic predictors, subacute indolent presentation (p = .001) and patchy or mass-like air-space consolidation on CT images (p = .002) were independently associated with good survival.
conclusionsApproximately one-third of alleged AFOP cases in the literature were diagnosed via non-surgical biopsy, but those cases had different symptomatic presentations and prognosis from surgically proven AFOP. Subacute indolent presentation and patchy or mass-like air-space consolidation at the presentation on CT images indicated a good prognosis in patients with AFOP. KEY POINTS: • Acute fibrinous and organizing pneumonia (AFOP) cases diagnosed via non-surgical biopsy had different symptomatic presentations and prognosis from surgically proven AFOP. • Subacute indolent presentation and patchy or mass-like air-space consolidation on CT images indicated a good prognosis in patients with acute fibrinous and organizing pneumonia.
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