ArticleCerebral cortex (New York, N.Y. : 1991)2021
Linked Social-Communication Dimensions and Connectivity in Functional Brain Networks in Autism Spectrum Disorder.
Article in Cerebral cortex (New York, N.Y. : 1991), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 22 citations in OpenAlex.
- A functional system-informed graph neural network framework to quantify interpretable brain dysfunction in ASD.Neural networks : the official journal of the International Neural Network Society · 2026Article
- Optimizing functional connectivity scanning conditions for predicting autistic traits.medRxiv : the preprint server for health sciences · 2026Article
- Neuroplasticity mechanisms of NDBIs in autism: a review from brain connectivity to behavioral improvement.European journal of medical research · 2026Review
- Optimizing functional connectivity scanning conditions for predicting autistic traits.Nature. Mental health · 2026Article
- Connectome-based symptom mapping and in silico related gene expression in children with autism and/or attention-deficit/hyperactivity disorder.Molecular psychiatry · 2026Article
- Connectome-based symptom mapping andmedRxiv : the preprint server for health sciences · 2024Article
- Interoception in Autism: A Narrative Review of Behavioral and Neurobiological Data.Psychology research and behavior management · 2024Review
- Delineating a Pathway for the Discovery of Functional Connectome Biomarkers of Autism.Advances in neurobiology · 2024Review
- A generalizable connectome-based marker of in-scan sustained attention in neurodiverse youth.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- The effect of physical exercise on disordered social communication in individuals with autism Spectrum disorder: a systematic review and meta-analysis of randomized controlled trials.Frontiers in pediatrics · 2023Review
- Functional Connectome-Based Predictive Modeling in Autism.Biological psychiatry · 2022Review
- Involvement of retinoic acid receptor α in the autistic-like behavior of rats with vitamin A deficiency by regulating neurexin 1 in the visual cortex: a mechanism study.Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2022Article
- Altered intrinsic brain activity and connectivity in unaffected parents of individuals with autism spectrum disorder: a resting-state fMRI study.Frontiers in human neuroscience · 2022Article
- A tale of two connectivities: intra- and inter-subject functional connectivity jointly enable better prediction of social abilities.Frontiers in neuroscience · 2022Article
- Alteration of Effective Connectivity in the Default Mode Network of Autism After an Intervention.Frontiers in neuroscience · 2021Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
Abstract
Much recent attention has been directed toward elucidating the structure of social interaction-communication dimensions and whether and how these symptom dimensions coalesce with each other in individuals with autism spectrum disorder (ASD). However, the underlying neurobiological basis of these symptom dimensions is unknown, especially the association of social interaction and communication dimensions with brain networks. Here, we proposed a method of whole-brain network-based regression to identify the functional networks linked to these symptom dimensions in a large sample of children with ASD. Connectome-based predictive modeling (CPM) was established to explore neurobiological evidence that supports the merging of communication and social interaction deficits into one symptom dimension (social/communication deficits). Results showed that the default mode network plays a core role in communication and social interaction dimensions. A primary sensory perceptual network mainly contributed to communication deficits, and high-level cognitive networks mainly contributed to social interaction deficits. CPM revealed that the functional networks associated with these symptom dimensions can predict the merged dimension of social/communication deficits. These findings delineate a link between brain functional networks and symptom dimensions for social interaction and communication and further provide neurobiological evidence supporting the merging of communication and social interaction deficits into one symptom dimension.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.