Evidence map›Paper›PMID 33791600›Full record

ArticleJournal of current science and technology2021

Perspective on the treatment of non-small cell lung cancer in the context of potential SARS-CoV-2 infection during the pandemic.

George Theodoropoulos, Katerina Albanis, Medhi Wangpaichitr

Open access · greenAbstract read
In one paragraph

Article in Journal of current science and technology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

George TheodoropoulosDepartment of Veterans Affairs, Miami VA Healthcare System, Research Service, Miami, FL.
Katerina AlbanisDepartment of Veterans Affairs, Miami VA Healthcare System, Research Service, Miami, FL.
Medhi WangpaichitrDepartment of Veterans Affairs, Miami VA Healthcare System, Research Service, Miami, FL.
Miami VA Healthcare System · US

Funding

Hi-jacking the kynurenine pathway: A new therapeutic approach used to treat cisplatin resistant lung cancer that evades immune surveillance and proliferates with increased ROS levelsI01BX004371 · VA · MIAMI VA HEALTH CARE SYSTEM · PI WANGPAICHITR, MEDHI · 2018 to 2025
–
BLRD VA I01 BX004371BLRD VA I01 BX005051
6 · The paper itself

Abstract

SARS-CoV-2 infections are rising at an alarming rate and various aspects of this pandemic must be quickly and adequately addressed in order to enhance effective healthcare delivery and protect at risk populations such as cancer patients. Preventing Covid-19 infection must be a top system wide priority to avoid mortality, and considerable financial and disease burden. Most cancer patients, and in particular those with tumors resistant to chemotherapy are particularly vulnerable to infection. In this review, we connect potential viral infection of patients with lung tumors that have somewhat quiescence the immune response in the tumor microenvironment and categorize target molecules in metabolism that may be used to identify at risk patients leading to more effective treatment regimens; keeping continuity of therapy and disease prevention during a very tumultuous period of time surrounding the pandemic.

Indexed as

ImmunosuppressiveLung cancerMetabolismSARS-CoV-2Tumor microenvironment

Identifiers

PMID33791600
PMCPMC8008947
OpenAlexW3133528940

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.