Evidence map›Paper›PMID 33791374›Full record

ArticleBioMed research international2021

Study on Damage Mechanism and Repair of Vascular Endothelial Cells Based on Ultrasound Technology.

Shuhao Deng, Quan Jiang, Xin Lu, Yuan Zhang

RetractedOpen access · hybridAbstract readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Shuhao DengDepartment of Ultrasound, Pudong New Area People's Hospital Affiliated to Shanghai University of Medicine & Health Sciences, Shanghai 201299, China.
Quan JiangDepartment of Ultrasound, Pudong New Area People's Hospital Affiliated to Shanghai University of Medicine & Health Sciences, Shanghai 201299, China.
Xin LuDepartment of Radiology, Pudong New Area People's Hospital Affiliated to Shanghai University of Medicine & Health Sciences, Shanghai 201299, China.
Yuan ZhangDepartment of Ultrasound, Pudong New Area People's Hospital Affiliated to Shanghai University of Medicine & Health Sciences, 490 Chuanhuan South Road, Pudong New Area, Shanghai, China.ORCID https://orcid.org/0000-0003-1801-6441
Shanghai University of Medicine and Health Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo detect the endothelial function of external iliac artery in rats with different stages of atherosclerosis by high-resolution ultrasound, so as to provide experimental methodological basis for evaluating the function of vascular endothelial cells by ultrasound.

methodsThe animals were randomly divided into the control group (

resultsThe protective effect of rosanilin on brain injury in rats with acute hypobaric hypoxia and its regulation on the expression of pAkt protein; ox-LDL inhibited the proliferation activity of EPCs in a concentration-dependent manner. The expression of KLF2 and S1PR1 in HAEC can be knocked down by small interfering RNA, and knocking down KLF2 can not only downregulate the expression of S1PR1 but also downregulate HAVEN. With the development of atherosclerosis, the endothelium-dependent relaxation function and endothelium-independent relaxation function of the control group and the atherosclerosis model at 4, 8, and 12 weeks were damaged in different degrees and gradually aggravated.

conclusionAtherosclerosis is a disease with both morphological and functional damage, and vascular endothelial function is damaged in the early stage with corresponding pathological changes. Ultrasound is an effective method to evaluate vascular endothelial function.

Indexed as

AtherosclerosisUltrasonic TherapyAnimalsDisease Models, AnimalEndothelial CellsFemaleKruppel-Like Transcription FactorsMaleNitric OxideRatsSphingosine-1-Phosphate ReceptorsKlf2 protein, ratKruppel-Like Transcription FactorsNitric OxideS1PR1 protein, ratSphingosine-1-Phosphate Receptors

Identifiers

PMID33791374
PMCPMC7984879
OpenAlexW3137722467

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.