Evidence map›Paper›PMID 33791348›Full record

ReviewFrontiers in cardiovascular medicine2021

Role of NFAT in the Progression of Diabetic Atherosclerosis.

Yaoyao Cai, Haipeng Yao, Zhen Sun, Ying Wang, Yunyun Zhao, Zhongqun Wang, Lihua Li

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 31 citations in OpenAlex.

  1. Frontiers in endocrinology · 2026
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  2. Review
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  9. [Metformin and lipopolysaccharide regulate transcription ofNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2022
    Article
  10. Review
  11. Article
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yaoyao CaiDepartment of Pathology, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Haipeng YaoDepartment of Cardiology, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Zhen SunDepartment of Cardiology, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Ying WangDepartment of Cardiology, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Yunyun ZhaoDepartment of Pathology, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Zhongqun WangDepartment of Cardiology, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Lihua LiDepartment of Pathology, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Affiliated Hospital of Jiangsu University · CNJiangsu University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nuclear factor of activated T cells (NFAT) is a transcription factor with a multidirectional regulatory function, that is widely expressed in immune cells, including cells in the cardiovascular system, and non-immune cells. A large number of studies have confirmed that calcineurin/NFAT signal transduction is very important in the development of vascular system and cardiovascular system during embryonic development, and plays some role in the occurrence of vascular diseases such as atherosclerosis, vascular calcification, and hypertension. Recent

Indexed as

atherosclerosisdiabetesNFATtargeted therapyvascular calcification

Identifiers

PMID33791348
PMCPMC8006278
OpenAlexW3133957470

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.