Evidence map›Paper›PMID 33791244›Full record

ReviewFrontiers in cellular and infection microbiology2021

Ibrexafungerp, a Novel Oral Triterpenoid Antifungal in Development: Overview of Antifungal Activity Against

Ahmed Gamal, Sherman Chu, Thomas S McCormick, Katyna Borroto-Esoda, David Angulo, Mahmoud A Ghannoum

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
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  10. Antifungal susceptibility and biofilm production of Candida species- causative agents of female genital tract infections.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Molecular association ofFrontiers in cellular and infection microbiology · 2023
    Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ahmed GamalDepartment of Dermatology, Case Western Reserve University, Cleveland, OH, United States.
Sherman ChuDepartment of Dermatology, Case Western Reserve University, Cleveland, OH, United States.
Thomas S McCormickDepartment of Dermatology, Case Western Reserve University, Cleveland, OH, United States.
Katyna Borroto-EsodaScynexis Inc., Jersey City, NJ, United States.
David AnguloScynexis Inc., Jersey City, NJ, United States.
Mahmoud A GhannoumDepartment of Dermatology, Case Western Reserve University, Cleveland, OH, United States.
Case Western Reserve University · USScynexis (United States) · USUniversity Hospitals of Cleveland · US

Funding

Identification of effective SCY-078 analogues targeting C. aurisR21AI143305 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI GHANNOUM, MAHMOUD A · 2019 to 2020
$441k
NIAID NIH HHS R21 AI143305
6 · The paper itself

Abstract

Systemic infections caused by

Indexed as

Candida glabrataTriterpenesAntifungal AgentsDrug Resistance, FungalGlycosidesHumansMicrobial Sensitivity TestsAntifungal AgentsGlycosidesibrexafungerpTriterpenesantifungalCandida glabrataibrexafungerpß-(1,3)-D-glucantriterpenoid class (fungerps)

Identifiers

PMID33791244
PMCPMC8006402
OpenAlexW3134830038

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.