Evidence map›Paper›PMID 33791203›Full record

ArticleFrontiers in oncology2021

Systematic Evaluation for the Influences of the SOX17/Notch Receptor Family Members on Reversing Enzalutamide Resistance in Castration-Resistant Prostate Cancer Cells.

Zhongbo Du, Luo Li, Wei Sun, Pingyu Zhu, Shulin Cheng, Xuesong Yang, Chunli Luo, Xiaodong Yu, Xiaohou Wu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Zhongbo DuDepartment of Clinical Medicine, North Sichuan Medical College, Nanchong, China.
Luo LiCenter for Immunology Research, Chongqing Medical University, Chongqing, China.
Wei SunDepartment of Urology, Fuling Center Hospital of Chongqing, Chongqing, China.
Pingyu ZhuDepartment of Clinical Medicine, North Sichuan Medical College, Nanchong, China.
Shulin ChengDepartment of Clinical Medicine, North Sichuan Medical College, Nanchong, China.
Xuesong YangDepartment of Urology, Affiliated Hospital of North Sichuan Medical College, Nanchong, China.
Chunli LuoKey Laboratory of Diagnostics Medicine Designated by the Ministry of Education, Chongqing Medical University, Chongqing, China.
Xiaodong YuDepartment of Clinical Medicine, North Sichuan Medical College, Nanchong, China.
Xiaohou WuDepartment of Urology, First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Chongqing Medical University · CNNorth Sichuan Medical University · CNAffiliated Hospital of North Sichuan Medical College · CNFuling Center Hospital of Chongqing · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The treatment of castration-resistant prostate cancer (CRPC) remains challenging due to the failure of androgen deprivation therapy (ADT); hence the search for other molecular therapeutic targets besides androgen receptor signaling is ongoing. This study systematically investigated the expression of SOX17 and Notch receptors in CRPC tissues and cells

Indexed as

castration-resistant prostate cancerenzalutamideNotch receptor family membersSOX17γ secretase inhibitors

Identifiers

PMID33791203
PMCPMC8006330
OpenAlexW3133908357

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.