Evidence map›Paper›PMID 33791072›Full record

ReviewOxidative medicine and cellular longevity2021

Studies on the Regulatory Roles and Related Mechanisms of lncRNAs in the Nervous System.

Zijian Zhou, Dake Qi, Quan Gan, Fang Wang, Bengang Qin, Jiachun Li, Honggang Wang, Dong Wang

Open access · hybridAbstract readReview
In one paragraph

Review in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Zijian ZhouThe Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, Guangdong, China.ORCID https://orcid.org/0000-0003-0526-5190
Dake QiMemorial University of Newfoundland School of Medicine, Newfoundland and Labrador, Canada.ORCID https://orcid.org/0000-0003-1353-6093
Quan GanThe Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, Guangdong, China.ORCID https://orcid.org/0000-0002-1355-0859
Fang WangUnion Hospital of Huazhong University of Science and Technology Shenzhen Hospital, Shenzhen, Guangdong, China.
Bengang QinThe First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0001-8402-2765
Jiachun LiThe Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, Guangdong, China.ORCID https://orcid.org/0000-0002-2994-0800
Honggang WangThe First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0002-9813-5266
Dong WangThe Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, Guangdong, China.ORCID https://orcid.org/0000-0002-2345-4457
Sun Yat-sen University · CNMemorial University of Newfoundland · CAUnion Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long noncoding RNAs (lncRNAs) have attracted extensive attention due to their regulatory role in various cellular processes. Emerging studies have indicated that lncRNAs are expressed to varying degrees after the growth and development of the nervous system as well as injury and degeneration, thus affecting various physiological processes of the nervous system. In this review, we have compiled various reported lncRNAs related to the growth and development of central and peripheral nerves and pathophysiology (including advanced nerve centers, spinal cord, and peripheral nervous system) and explained how these lncRNAs play regulatory roles through their interactions with target-coding genes. We believe that a full understanding of the regulatory function of lncRNAs in the nervous system will contribute to understand the molecular mechanism of changes after nerve injury and will contribute to discover new diagnostic markers and therapeutic targets for nerve injury diseases.

Indexed as

AnimalsCell DifferentiationHumansNerve RegenerationNervous SystemNervous System DiseasesNeural Stem CellsRNA, Long NoncodingRNA, Long Noncoding

Identifiers

PMID33791072
PMCPMC7984887
OpenAlexW3136563833

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.