Evidence map›Paper›PMID 33790865›Full record

ArticleFrontiers in endocrinology2021

Reduced Vitellogenesis and Female Fertility in Gper Knockout Zebrafish.

Xin-Jun Wu, Marcus Jermaul Williams, Kimberly Ann Kew, Aubrey Converse, Peter Thomas, Yong Zhu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xin-Jun WuDepartment of Biology, East Carolina University, Greenville, NC, United States.
Marcus Jermaul WilliamsDepartment of Biology, East Carolina University, Greenville, NC, United States.
Kimberly Ann KewDepartment of Biochemistry and Molecular Biology, Brody School of Medicine, East Carolina University, Greenville, NC, United States.
Aubrey ConverseMarine Science Institute, University of Texas at Austin, Port Aransas, TX, United States.
Peter ThomasMarine Science Institute, University of Texas at Austin, Port Aransas, TX, United States.
Yong ZhuDepartment of Biology, East Carolina University, Greenville, NC, United States.
East Carolina University · US

Funding

To characterize nongenomic progestin receptors via knockouts in zebrafishR15GM100461 · NIGMS · EAST CAROLINA UNIVERSITY · PI ZHU, YONG · 2013 to 2017
$757k
NIGMS NIH HHS R15 GM100461
6 · The paper itself

Abstract

The role G-protein coupled estrogen receptor (GPER) plays in vertebrate reproduction remains controversial. To investigate GPER's reproductive role, we generated a gper zebrafish mutant line (

Indexed as

AnimalsCell MembraneErbB ReceptorsEstrogensFemaleFertilityFishesMetabolomicsMutationOocytesOvarian FollicleOvulationReceptors, EstrogenReceptors, G-Protein-CoupledVitellogenesisVitellogeninsErbB ReceptorsEstrogensgper1 protein, zebrafishReceptors, EstrogenReceptors, G-Protein-CoupledVitellogeninsZebrafish Proteinsepidermal growth factor receptor (Egfr)G-protein coupled estrogen receptor (Gper)oocyte growthreduced fertilityvitellogenin

Identifiers

PMID33790865
PMCPMC8006473
OpenAlexW3135868278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.