Evidence map›Paper›PMID 33790864›Full record

ReviewFrontiers in endocrinology2021

Traumatic Brain Injury as Frequent Cause of Hypopituitarism and Growth Hormone Deficiency: Epidemiology, Diagnosis, and Treatment.

Valentina Gasco, Valeria Cambria, Fabio Bioletto, Ezio Ghigo, Silvia Grottoli

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Observational
  6. Review
  7. Review
  8. Bidirectional Interaction Between the Brain and Bone in Traumatic Brain Injury.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Metabolic and quality of life effects of growth hormone replacement in patients with TBI and AGHD: A pilot study.Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society · 2023
    Observational
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Valentina GascoDivision of Endocrinology, Diabetes and Metabolism, University of Turin, Turin, Italy.
Valeria CambriaDivision of Endocrinology, Diabetes and Metabolism, University of Turin, Turin, Italy.
Fabio BiolettoDivision of Endocrinology, Diabetes and Metabolism, University of Turin, Turin, Italy.
Ezio GhigoDivision of Endocrinology, Diabetes and Metabolism, University of Turin, Turin, Italy.
Silvia GrottoliDivision of Endocrinology, Diabetes and Metabolism, University of Turin, Turin, Italy.
University of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traumatic brain injury (TBI)-related hypopituitarism has been recognized as a clinical entity for more than a century, with the first case being reported in 1918. However, during the 20

Indexed as

AnimalsBody CompositionBone DensityBrain InjuriesBrain Injuries, TraumaticCardiovascular DiseasesGrowth HormoneHormone Replacement TherapyHuman Growth HormoneHumansHypopituitarismHypothalamusHypothyroidismInsulin-Like Growth Factor IPituitary GlandQuality of LifeGrowth HormoneHuman Growth HormoneInsulin-Like Growth Factor Ibrain damagegrowth hormone deficiencyhypopituitarismpituitarytraumatic brain injury

Identifiers

PMID33790864
PMCPMC8005917
OpenAlexW3136194887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.