Evidence map›Paper›PMID 33790803›Full record

ArticleFrontiers in physiology2021

Inhibiting Mitochondrial Cytochrome

Ekta J Shah, Maik Hüttemann, Thomas H Sanderson, Katherine Gurdziel, Douglas M Ruden

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Drosophila as a model to explore secondary injury cascades after traumatic brain injury.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2021
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ekta J ShahDepartment of Pharmacology, Wayne State University School of Medicine, Detroit, MI, United States.
Maik HüttemannCenter for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI, United States.
Thomas H SandersonDepartment of Emergency Medicine, University of Michigan Medical School, Ann Arbor, MI, United States.
Katherine GurdzielOffice of the Vice President of Research, Wayne State University, Detroit, MI, United States.
Douglas M RudenDepartment of Pharmacology, Wayne State University School of Medicine, Detroit, MI, United States.
Wayne State University · USUniversity of Michigan–Ann Arbor · US

Funding

Understanding Breastfeeding Practices Among ECHO Cohort Participants Before and During/After the COVID-19 PandemicUH3OD023285 · OD · MICHIGAN STATE UNIVERSITY · PI Charles James Barone, MICHAEL R. ELLIOTT · 2018 to 2026
$24.5M
Prenatal Exposures and Child Health Outcomes: A Statewide StudyUG3OD023285 · OD · MICHIGAN STATE UNIVERSITY · PI BARONE, CHARLES JAMES, ELLIOTT, MICHAEL R. · 2016 to 2024
$12.9M
Pilot Project ProgramP30ES020957 · NIEHS · WAYNE STATE UNIVERSITY · PI RUNGE-MORRIS, MELISSA A · 2014 to 2021
$10.1M
QTL AND MICROARRAY MAPPING LEAD SENSITIVITY GENESR01ES012933 · NIEHS · WAYNE STATE UNIVERSITY · PI RUDEN, DOUGLAS M · 2004 to 2015
$3.4M
Non-invasive mitochondrial modulation therapy for ischemic strokeR01NS120322 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HUETTEMANN, MAIK, SANDERSON, THOMAS HUDSON · 2021 to 2025
$2.3M
Infant NeuroLUX: A Novel Non-invasive Therapeutic Device for Neonatal Hypoxic Brain InjuryR42NS105238 · NINDS · MITOVATION, INC. · PI HUETTEMANN, MAIK, SANDERSON, THOMAS HUDSON · 2018 to 2020
$1.8M
NovaSeq Shared Instrumentation Grant for Wayne State UniversityS10OD025170 · OD · WAYNE STATE UNIVERSITY · PI RUDEN, DOUGLAS M · 2018 to 2018
$600k
Effects of Lead on Neuronal Differentiation in Human Embryonic Stem CellsR21ES021983 · NIEHS · WAYNE STATE UNIVERSITY · PI RUDEN, DOUGLAS M · 2012 to 2013
$413k
NIEHS NIH HHS P30 ES020957NIEHS NIH HHS R01 ES012933NIEHS NIH HHS R21 ES021983NIH HHS S10 OD025170NIH HHS UG3 OD023285NIH HHS UH3 OD023285NINDS NIH HHS R01 NS120322NINDS NIH HHS R42 NS105238
6 · The paper itself

Abstract

Traumatic brain injuries (TBIs) caused by a sudden impact to the head alter behavior and impair physical and cognitive function. Besides the severity, type and area of the brain affected, the outcome of TBI is also influenced by the patient's biological sex. Previous studies reporting mitochondrial dysfunction mainly focused on exponential reactive oxygen species (ROS) generation, increased mitochondrial membrane potential, and altered mitochondrial dynamics as a key player in the outcome to brain injury. In this study, we evaluated the effect of a near-infrared (NIR) light exposure on gene expression in a

Indexed as

gene expressionmitochondrianear-infrared lightsex-differencestraumatic brain injury

Identifiers

PMID33790803
PMCPMC8005633
OpenAlexW3136158794

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.