Evidence map›Paper›PMID 33790751›Full record

ArticleFrontiers in human neuroscience2021

A Neuromotor to Acoustical Jaw-Tongue Projection Model With Application in Parkinson's Disease Hypokinetic Dysarthria.

Andrés Gómez, Pedro Gómez, Daniel Palacios, Victoria Rodellar, Víctor Nieto, Agustín Álvarez, Athanasios Tsanas

Open access · goldAbstract read
In one paragraph

Article in Frontiers in human neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Andrés GómezOld Medical School, Medical School, Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.
Pedro GómezNeuSpeLab, Center for Biomedical Technology, Universidad Politécnica de Madrid, Madrid, Spain.
Daniel PalaciosNeuSpeLab, Center for Biomedical Technology, Universidad Politécnica de Madrid, Madrid, Spain.
Victoria RodellarNeuSpeLab, Center for Biomedical Technology, Universidad Politécnica de Madrid, Madrid, Spain.
Víctor NietoNeuSpeLab, Center for Biomedical Technology, Universidad Politécnica de Madrid, Madrid, Spain.
Agustín ÁlvarezNeuSpeLab, Center for Biomedical Technology, Universidad Politécnica de Madrid, Madrid, Spain.
Athanasios TsanasOld Medical School, Medical School, Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.
Universidad Politécnica de Madrid · ESUniversidad Rey Juan Carlos · ESUniversity of Edinburgh · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe present work proposes the study of the neuromotor activity of the masseter-jaw-tongue articulation during diadochokinetic exercising to establish functional statistical relationships between surface Electromyography (sEMG), 3D Accelerometry (3DAcc), and acoustic features extracted from the speech signal, with the aim of characterizing Hypokinetic Dysarthria (HD). A database of multi-trait signals of recordings from an age-matched control and PD participants are used in the experimental study. HYPOTHESIS: The main assumption is that information between sEMG and 3D acceleration, and acoustic features may be quantified using linear regression methods.

methodsRecordings from a cohort of eight age-matched control participants (4 males, 4 females) and eight PD participants (4 males, 4 females) were collected during the utterance of a diadochokinetic exercise (the fast repetition of diphthong [aI]). The dynamic and acoustic absolute kinematic velocities produced during the exercises were estimated by acoustic filter inversion and numerical integration and differentiation of the speech signal. The amplitude distributions of the absolute kinematic and acoustic velocities (AKV and AFV) are estimated to allow comparisons in terms of Mutual Information.

resultsThe regression results show the relationships between sEMG and dynamic and acoustic estimates. The projection methodology may help in understanding the basic neuromotor muscle activity regarding neurodegenerative speech in remote monitoring neuromotor and neurocognitive diseases using speech as the vehicular tool, and in the study of other speech-related disorders. The study also showed strong and significant cross-correlations between articulation kinematics, both for the control and the PD cohorts. The absolute kinematic variables presents an observable difference for the PD participants compared to the control group.

conclusionKinematic distributions derived from acoustic analysis may be useful biomarkers toward characterizing HD in neuromotor disorders providing new insights into PD.

Indexed as

hypokinetic dysarthrianeuromechanicsneuromotor disordersspeech kinematicssurface electromyography

Identifiers

PMID33790751
PMCPMC8005556
OpenAlexW3136322650

What OpenQuestion holds

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.