Evidence map›Paper›PMID 33790743›Full record

ArticleFrontiers in cellular neuroscience2021

The P2X

Keith E Campagno, Claire H Mitchell

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 82 citations in OpenAlex.

  1. Review
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  3. Biological psychiatry global open science · 2026
    Article
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  6. Illuminating proinflammatory myeloid cells with PET tracers targeting GPR84.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
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5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Keith E CampagnoDepartment of Basic and Translational Science, University of Pennsylvania, Philadelphia, PA, United States.
Claire H MitchellDepartment of Basic and Translational Science, University of Pennsylvania, Philadelphia, PA, United States.
Translational Therapeutics (United States) · US

Funding

NRSA Training CoreTL1TR001880 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI MEAGHER, EMMA ANNE · 2016 to 2025
$10.0M
Purines and the Health of Retinal Ganglion CellsR01EY015537 · NEI · UNIVERSITY OF PENNSYLVANIA · PI MITCHELL, CLAIRE H · 2005 to 2023
$6.7M
REGULATION OF LYSOSOMAL PH IN RPE CELLSR01EY013434 · NEI · UNIVERSITY OF PENNSYLVANIA · PI MITCHELL, CLAIRE H · 2002 to 2020
$5.3M
RESEARCH ON NORMAL AND ABNORMAL MECHANISMS OF VISIONST32EY007035 · NEI · UNIVERSITY OF PENNSYLVANIA · PI Diego Contreras, Jessica I.W. Morgan · 1985 to 2026
$4.9M
NCATS NIH HHS TL1 TR001880NEI NIH HHS R01 EY013434NEI NIH HHS R01 EY015537NEI NIH HHS T32 EY007035
6 · The paper itself

Abstract

Microglial cells regulate neural homeostasis by coordinating both immune responses and clearance of debris, and the P2X

Indexed as

autophagycathepsin BlysosomesmicroglianeuroinflammationNLRP3P2X7phagocytosis

Identifiers

PMID33790743
PMCPMC8005553
OpenAlexW3137602493

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.