Evidence map›Paper›PMID 33790689›Full record

ArticleGreen chemistry : an international journal and green chemistry resource : GC2020

Biological upgrading of 3,6-anhydro-L-galactose from agarose to a new platform chemical.

Dong Hyun Kim, Jing-Jing Liu, Jae Won Lee, Jeffrey G Pelton, Eun Ju Yun, Sora Yu, Yong-Su Jin, Kyoung Heon Kim

Open access · greenAbstract read
In one paragraph

Article in Green chemistry : an international journal and green chemistry resource : GC, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Characterization of Cold-TolerantMicroorganisms · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Dong Hyun KimDepartment of Biotechnology, Graduate School, Korea University, Seoul 02841, South Korea.
Jing-Jing LiuCarl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Jae Won LeeCarl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Jeffrey G PeltonQB3 Institute, University of California, Berkeley, CA, USA.
Eun Ju YunDepartment of Biotechnology, Graduate School, Korea University, Seoul 02841, South Korea.
Sora YuDepartment of Biotechnology, Graduate School, Korea University, Seoul 02841, South Korea.
Yong-Su JinCarl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Kyoung Heon KimDepartment of Biotechnology, Graduate School, Korea University, Seoul 02841, South Korea.
Korea University · KRUniversity of Illinois Urbana-Champaign · USQB3 · US

Funding

Proposal for Central California 900 MHZ NMR SpectrometerP41GM068933 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI WEMMER, DAVID E · 2003 to 2007
$5.9M
NIGMS NIH HHS P41 GM068933
6 · The paper itself

Abstract

Recently, the utilization of renewable biomass instead of fossil fuels for producing fuels and chemicals is receiving much attention due to the global climate change. Among renewable biomass, marine algae are gaining importance as third generation biomass feedstocks owing to their advantages over lignocellulose. Particularly, red macroalgae have higher carbohydrate contents and simpler carbohydrate compositions than other marine algae. In red macroalgal carbphydrates, 3,6-anhydro-L-galactose (AHG) is the main sugar composing agarose along with D-galactose. However, AHG is not a common sugar and is chemically unstable. Thus, not only AHG but also red macroalgal biomass itself cannot be efficiently converted or utilized. Here, we biologically upgraded AHG to a new platform chemical, its sugar alcohol form, 3,6-anhydro-l-galactitol (AHGol), an anhydrohexitol. To accomplish this, we devised an integrated process encompassing a chemical hydrolysis process for producing agarobiose (AB) from agarose and a biological process for converting AB to AHGol using metabolically engineered

Identifiers

PMID33790689
PMCPMC8009285
OpenAlexW3007278227

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.