Evidence map›Paper›PMID 33790662›Full record

ReviewJournal of experimental pharmacology2021

Experimental Disease-Modifying Agents for Frontotemporal Lobar Degeneration.

Marcello Giunta, Eino Solje, Fabrizio Gardoni, Barbara Borroni, Alberto Benussi

Open access · goldAbstract readReview
In one paragraph

Review in Journal of experimental pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Identification of a novel mutation in MEF2C gene in an atypical patient with frontotemporal lobar degeneration.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Marcello GiuntaNeurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
Eino SoljeInstitute of Clinical Medicine - Neurology, University of Eastern Finland, Kuopio, Finland.
Fabrizio GardoniDepartment of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy.
Barbara BorroniNeurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
Alberto BenussiNeurology Unit, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
University of Brescia · ITUniversity of Eastern Finland · FIUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Frontotemporal dementia is a clinically, genetically and pathologically heterogeneous neurodegenerative disorder, enclosing a wide range of different pathological entities, associated with the accumulation of proteins such as tau and TPD-43. Characterized by a high hereditability, mutations in three main genes,

Indexed as

C9orf72frontotemporal dementiafrontotemporal lobar degenerationGRNMAPTtauTDP-43therapy

Identifiers

PMID33790662
PMCPMC8005747
OpenAlexW3139392115

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.