Evidence map›Paper›PMID 33790643›Full record

Trial reportLocal and regional anesthesia2021

Levobupivacaine Consumption in Automated Intermittent Bolus in Ultrasound Guided Subparaneural Sciatic Nerve Catheters: A Prospective Double-Blind Randomized Trial.

Margaretha B Breebaart, Jordi Branders, Luc Sermeus, Sultan Termurziev, Helene Camerlynck, Lennert Van Putte, Marnik Van Putte Minelli, Stefan De Hert

Open access · goldAbstract readCase ReportsClinical Trial
In one paragraph

Trial report in Local and regional anesthesia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Margaretha B BreebaartFaculty of Medicine and Health Sciences, Antwerp University, Wilrijk, Belgium.ORCID 0000-0002-7538-3013
Jordi BrandersDepartment of Anesthesia, Antwerp University Hospital, Edegem, Belgium.
Luc SermeusDepartment of Anesthesiology, St. Luc University Hospital, Brussels, Belgium.
Sultan TermurzievDepartment of Anesthesia, Antwerp University Hospital, Edegem, Belgium.
Helene CamerlynckDepartment of Anesthesia, Antwerp University Hospital, Edegem, Belgium.
Lennert Van PutteFaculty of Medicine and Health Sciences, Antwerp University, Wilrijk, Belgium.ORCID 0000-0003-0024-5553
Marnik Van Putte MinelliFaculty of Medicine and Health Sciences, Antwerp University, Wilrijk, Belgium.
Stefan De HertDepartment of Anesthesia and Perioperative Medicine, Ghent University Hospital, Ghent, Belgium.ORCID 0000-0002-6624-1646
Antwerp University Hospital · BEUniversity of Antwerp · BEGhent University Hospital · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeContinuous sciatic nerve blocks have proven benefits for postoperative analgesia after foot surgery. However, the optimal mode of administration remains a point of debate. Ultrasound guided subparaneural injection accelerates onset time and increases duration after a single shot sciatic nerve block. This double blind prospective randomized trial compares the 48-hour local anesthetic (LA) dose consumption of an automated intermittent bolus technique to a continuous infusion regimen in a subparaneural sciatic nerve catheter after hallux valgus surgery. PATIENTS AND

methodsPatients scheduled for hallux valgus surgery were randomized to receive either a continuous infusion of levobupivacaine 0.125% at 5mL/h (group A) or an intermittent automated bolus of 9.8 mL every 2 hours with a background of 0.1 mL/h (group B), both with a PCA bolus of 6 mL and lockout of 30 minutes. The 48 hour LA consumption, PCA boluses, Numeric Rating Scale (NRS), satisfaction and return of normal sensation were recorded.

resultsSixteen patients were excluded because of protocol violation or technical problems and 42 patients remained for analysis. The 48 hour ropivacaine consumption was higher in group A (293 ±60 mL) than group B (257±33 mL). The median and highest NRS scores and patient satisfaction were not statistically different between groups. Normal sensation returned after 75 ± 22 hours (group A) and 70 ± 17 hours (group B).

conclusionProgrammed bolus administration in subparaneural sciatic nerve catheters reduces LA consumption 48 hours after surgery with equal analgesia and patient satisfaction. Return of sensation is variable and can last more than 75 hours.

Indexed as

levobupivacainelocal anestheticslocoregional anesthesiaorthopedic surgerypostoperative painsciatic nerve block

Identifiers

PMID33790643
PMCPMC8007557
OpenAlexW3136314691

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.