Evidence map›Paper›PMID 33790365›Full record

ArticleScientific reports2021

Risk factors on admission associated with hospital length of stay in patients with COVID-19: a retrospective cohort study.

Anping Guo, Jin Lu, Haizhu Tan, Zejian Kuang, Ying Luo, Tian Yang, Junlan Xu, Jishuang Yu, Canhong Wen, Aizong Shen

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Anping Guo *Department of Pharmacy, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, People's Republic of China.
Jin Lu *Department of Pharmacy, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, People's Republic of China.
Haizhu Tan *Shantou University Medical College, Shantou, Guangdong, People's Republic of China.
Zejian KuangThe Second Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong, People's Republic of China.
Ying LuoInfectious Diseases Department of the First Affiliated Hospital, University of Science and Technology of China, Hefei, Anhui, People's Republic of China.
Tian YangInfectious Diseases Department of the First Affiliated Hospital, University of Science and Technology of China, Hefei, Anhui, People's Republic of China.
Junlan XuInfectious Diseases Department of the First Affiliated Hospital, University of Science and Technology of China, Hefei, Anhui, People's Republic of China.
Jishuang YuInfectious Diseases Department of the First Affiliated Hospital, University of Science and Technology of China, Hefei, Anhui, People's Republic of China.
Canhong WenDepartment of Statistics and Finance, School of Management, University of Science and Technology of China, Hefei, 230026, Anhui, People's Republic of China. wench@ustc.edu.cn.ORCID 0000-0003-0220-9986
Aizong ShenDepartment of Pharmacy, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, People's Republic of China. shengaizongah@126.com.
University of Science and Technology of China · CNShantou University · CN

Funding

National Natural Science Foundation of China (National Science Foundation of China) 11801540Natural Science Foundation of Guangdong [2017A030310572]and Fundamental Research Funds for the Central Universities WK2040000016Natural Science Foundation of Guangdong [2017A030310572]and Fundamental Research Funds for the Central Universities WK2040170015
6 · The paper itself

Abstract

Treating patients with COVID-19 is expensive, thus it is essential to identify factors on admission associated with hospital length of stay (LOS) and provide a risk assessment for clinical treatment. To address this, we conduct a retrospective study, which involved patients with laboratory-confirmed COVID-19 infection in Hefei, China and being discharged between January 20 2020 and March 16 2020. Demographic information, clinical treatment, and laboratory data for the participants were extracted from medical records. A prolonged LOS was defined as equal to or greater than the median length of hospitable stay. The median LOS for the 75 patients was 17 days (IQR 13-22). We used univariable and multivariable logistic regressions to explore the risk factors associated with a prolonged hospital LOS. Adjusted odds ratios (aORs) and 95% confidence intervals (CIs) were estimated. The median age of the 75 patients was 47 years. Approximately 75% of the patients had mild or general disease. The univariate logistic regression model showed that female sex and having a fever on admission were significantly associated with longer duration of hospitalization. The multivariate logistic regression model enhances these associations. Odds of a prolonged LOS were associated with male sex (aOR 0.19, 95% CI 0.05-0.63, p = 0.01), having fever on admission (aOR 8.27, 95% CI 1.47-72.16, p = 0.028) and pre-existing chronic kidney or liver disease (aOR 13.73 95% CI 1.95-145.4, p = 0.015) as well as each 1-unit increase in creatinine level (aOR 0.94, 95% CI 0.9-0.98, p = 0.007). We also found that a prolonged LOS was associated with increased creatinine levels in patients with chronic kidney or liver disease (p < 0.001). In conclusion, female sex, fever, chronic kidney or liver disease before admission and increasing creatinine levels were associated with prolonged LOS in patients with COVID-19.

Indexed as

Length of StayAdolescentAdultAgedAged, 80 and overChildChild, PreschoolChinaComorbidityCOVID-19CreatinineFemaleFeverHospitalizationHumansMaleCreatinine

Identifiers

PMID33790365
PMCPMC8012638
OpenAlexW3152215807

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.