ArticleOccupational and environmental medicine2021
Occupations and exposure events in acute and subacute irritant-induced asthma.
Article in Occupational and environmental medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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6 citing papers in PubMed, 24 citations in OpenAlex.
- Nasal mucosa micronuclei as early biomarkers of effect in workers exposed to airborne pollutants: a literature overview.Archives of toxicology · 2025Review
- Occupational Exposure Patterns to Disinfectants and Cleaning Products and Its Association With Asthma Among French Healthcare Workers.American journal of industrial medicine · 2025Article
- Assessing the Application of Physiologically Based Pharmacokinetic Models in Acute Chemical Incidents.Journal of xenobiotics · 2025Article
- Ecuadorian Provinces with High Morbidity and Mortality Rates Due to Asthma among the Working-Age Population: An Ecological Study to Promote Respiratory Health.International journal of environmental research and public health · 2024Article
- Occupational lung disease: when should I think of it and why is it important?Breathe (Sheffield, England) · 2023Review
- Respiratory afflictions during hairdressing jobs: case history and clinical evaluation of a large symptomatic case series.Journal of occupational medicine and toxicology (London, England) · 2022Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExposures leading to irritant-induced asthma (IIA) are poorly documented.
methodsWe retrospectively screened the medical records of patients with IIA diagnosed in an occupational medicine clinic during 2000-2018. We classified the cases into acute (onset after single exposure) and subacute (onset after multiple exposures) IIA. We analysed in detail, occupations, causative agents and their air levels in the workplace, exposure events and the root causes of high exposure.
resultsAltogether 69 patients were diagnosed with IIA, 30 with acute and 39 with subacute IIA. The most common occupational groups were industrial operators (n=23, 33%), metal and machinery workers (n=16, 11%) and construction workers (n=12, 8%). Among industrial operators significantly more cases had subacute IIA than acute IIA (p=0.002). Forty cases (57%) were attributable to some type of corrosive acidic or alkaline chemical. Acute IIA followed accidents at work in different types of occupation, while subacute IIA was typical among industrial operators performing their normal work tasks under poor work hygiene conditions. The most common root cause was lack of information or false guidance in acute IIA (n=11, 36%) and neglect of workplace hygiene measures in subacute IIA (n=29, 74%).
conclusionsAccidents are the main causes of acute IIA, whereas subacute IIA can develop in normal work in risk trades with poor work hygiene. Airborne strong acids or bases seem to be the most important causative agents of acute and subacute IIA. The different risk profiles of acute and subacute IIA should be considered in the prevention and identification of the cases.
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