Evidence map›Paper›PMID 33790011›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

c-di-AMP, a likely master regulator of bacterial K

Tatiana B Cereija, João P L Guerra, João M P Jorge, João H Morais-Cabral

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Ecological plasticity ofMicrobiology spectrum · 2026
    Article
  3. Review
  4. Article
  5. Regulation of potassium homeostasis inFrontiers in microbiology · 2026
    Article
  6. TrkA ofMicrobiology (Reading, England) · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Bacterial cell volume regulation and the importance of cyclic di-AMP.Microbiology and molecular biology reviews : MMBR · 2024
    Review
  15. Article
  16. c-di-AMP determines the hierarchical organization of bacterial RCK proteins.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  17. Article
  18. Cyclic di-AMP traps proton-coupled KNature communications · 2023
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tatiana B CereijaInstituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135 Porto, Portugal.ORCID 0000-0002-7176-0205
João P L GuerraInstituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135 Porto, Portugal.ORCID 0000-0001-5441-9446
João M P JorgeInstituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135 Porto, Portugal.ORCID 0000-0001-7075-5589
João H Morais-CabralInstituto de Biologia Molecular e Celular, Universidade do Porto, 4200-135 Porto, Portugal; jcabral@ibmc.up.pt.ORCID 0000-0002-4461-9716
Universidade do Porto · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

bis-(3',5')-cyclic diadenosine monophosphate (c-di-AMP) is a second messenger with roles in virulence, cell wall and biofilm formation, and surveillance of DNA integrity in many bacterial species, including pathogens. Strikingly, it has also been proposed to coordinate the activity of the components of K

Indexed as

Bacillus subtilisBacterial ProteinsBinding SitesCyclic AMPHomeostasisPotassiumPotassium-Hydrogen AntiportersProtein BindingBacterial ProteinsCyclic AMPPotassiumPotassium-Hydrogen AntiportersB. subtilisK+/H+ antiporterKhtTKhtTURCK domain

Identifiers

PMID33790011
PMCPMC8040634
OpenAlexW3146982019

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.