Evidence map›Paper›PMID 33789991›Full record

ArticleJournal of virology2021

Mucosal Priming with a Recombinant Influenza A Virus-Vectored Vaccine Elicits T-Cell and Antibody Responses to HIV-1 in Mice.

Jinlin Wang, Tao Shu, Weiqi Deng, Yali Zheng, Min Liao, Xianmiao Ye, Lujie Han, Ping He, Xuehua Zheng, Ting Li and 7 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Jinlin Wang *State Key Laboratory of Respiratory Diseases, Guangdong Laboratory of Computational Biomedicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
Tao Shu *State Key Laboratory of Respiratory Diseases, Guangdong Laboratory of Computational Biomedicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
Weiqi DengState Key Laboratory of Respiratory Diseases, Guangdong Laboratory of Computational Biomedicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
Yali ZhengState Key Laboratory of Respiratory Diseases, Guangdong Laboratory of Computational Biomedicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
Min LiaoState Key Laboratory of Respiratory Diseases, Guangdong Laboratory of Computational Biomedicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
Xianmiao YeState Key Laboratory of Respiratory Diseases, Guangdong Laboratory of Computational Biomedicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
Lujie HanGuangzhou nBiomed Ltd., Guangzhou, China.
Ping HeState Key Laboratory of Respiratory Diseases, Guangdong Laboratory of Computational Biomedicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
Xuehua ZhengState Key Laboratory of Respiratory Diseases, Guangdong Laboratory of Computational Biomedicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
Ting LiState Key Laboratory of Respiratory Diseases, Guangdong Laboratory of Computational Biomedicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
Ying FengState Key Laboratory of Respiratory Diseases, Guangdong Laboratory of Computational Biomedicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
Fengyu HuGuangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China.
Pingchao LiState Key Laboratory of Respiratory Diseases, Guangdong Laboratory of Computational Biomedicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
Caijun SunSchool of Public Health (Shenzhen), Sun Yat-sen University, Guangzhou, China.
Ling Chen *State Key Laboratory of Respiratory Diseases, Guangdong Laboratory of Computational Biomedicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.ORCID 0000-0003-1485-1626
Feng Li *Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, China gz8h_lifeng@126.com feng_liqiang@gibh.ac.cn.
Liqiang Feng *State Key Laboratory of Respiratory Diseases, Guangdong Laboratory of Computational Biomedicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China gz8h_lifeng@126.com feng_liqiang@gibh.ac.cn.ORCID 0000-0001-6811-2074
Chinese Academy of Sciences · CNGuangzhou Eighth People's Hospital · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recombinant influenza A viral (IAV) vectors are potential to stimulate systemic and mucosal immunity, but the packaging capacity is limited and only one or a few epitopes can be carried. Here, we report the generation of a replication-competent IAV vector that carries a full-length HIV-1

Indexed as

Immunity, MucosalAdenoviridaeAIDS VaccinesAnimalsAntibodies, ViralBronchoalveolar Lavage FluidCD8-Positive T-LymphocytesFemaleGenes, gagHIV-1HIV AntibodiesHIV Core Protein p24HIV InfectionsImmunity, CellularImmunization, SecondaryImmunogenicity, VaccineAIDS VaccinesAntibodies, ViralHIV AntibodiesHIV Core Protein p24Immunoglobulin AImmunoglobulin Gp24 protein, Human Immunodeficiency Virus Type 1Vaccines, Syntheticantibodyhuman immunodeficiency virus type 1mucosal immune responserecombinant influenza A virusT cellvaccinevector

Identifiers

PMID33789991
PMCPMC8315921
OpenAlexW3145792818

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.