Evidence map›Paper›PMID 33789960›Full record

ArticleJournal of clinical microbiology2021

A Bioinformatics Whole-Genome Sequencing Workflow for Clinical Mycobacterium tuberculosis Complex Isolate Analysis, Validated Using a Reference Collection Extensively Characterized with Conventional Methods and

Bert Bogaerts, Thomas Delcourt, Karine Soetaert, Samira Boarbi, Pieter-Jan Ceyssens, Raf Winand, Julien Van Braekel, Sigrid C J De Keersmaecker, Nancy H C Roosens, Kathleen Marchal and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Microbial genomics · 2025
    Pooled it
  2. Article
  3. Article
  4. Draft genomes of three strains ofMicrobiology resource announcements · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Aerosolization of viableProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  13. Genomic comparison betweenFrontiers in veterinary science · 2024
    Article
  14. Journal of clinical microbiology · 2023
    Article
  15. Article
  16. Article
  17. Multiple CD59 Polymorphisms in Chinese Patients withJournal of immunology research · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Bert Bogaerts *Transversal Activities in Applied Genomics, Sciensano, Brussels, Belgium.ORCID 0000-0003-2806-4033
Thomas Delcourt *Transversal Activities in Applied Genomics, Sciensano, Brussels, Belgium.
Karine SoetaertBacterial Diseases, Sciensano, Brussels, Belgium.
Samira BoarbiBacterial Diseases, Sciensano, Brussels, Belgium.
Pieter-Jan CeyssensBacterial Diseases, Sciensano, Brussels, Belgium.
Raf WinandTransversal Activities in Applied Genomics, Sciensano, Brussels, Belgium.
Julien Van BraekelTransversal Activities in Applied Genomics, Sciensano, Brussels, Belgium.
Sigrid C J De KeersmaeckerTransversal Activities in Applied Genomics, Sciensano, Brussels, Belgium.
Nancy H C RoosensTransversal Activities in Applied Genomics, Sciensano, Brussels, Belgium.
Kathleen MarchalDepartment of Information Technology, Internet Technology and Data Science Lab (IDLab), Interuniversity Microelectronics Centre (IMEC), Ghent University, Ghent, Belgium.
Vanessa Mathys *Bacterial Diseases, Sciensano, Brussels, Belgium.
Kevin Vanneste *Transversal Activities in Applied Genomics, Sciensano, Brussels, Belgium kevin.vanneste@sciensano.be.
Sciensano (Belgium) · BEGhent University · BE

Funding

Wellcome Trust
6 · The paper itself

Abstract

The use of whole-genome sequencing (WGS) for routine typing of bacterial isolates has increased substantially in recent years. For

Indexed as

Mycobacterium tuberculosisComputational BiologyComputer SimulationGenome, BacterialHumansPolymorphism, Single NucleotideWhole Genome SequencingWorkflowantimicrobial resistanceMycobacterium tuberculosisnational reference centerpublic healthsingle nucleotide polymorphismvalidationwhole genome sequencing

Identifiers

PMID33789960
PMCPMC8316078
OpenAlexW3140594987

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.