Evidence map›Paper›PMID 33789653›Full record

ReviewJournal of nanobiotechnology2021

Engineering of bioactive metal sulfide nanomaterials for cancer therapy.

Weidong Fei, Meng Zhang, Xiaoyu Fan, Yiqing Ye, Mengdan Zhao, Caihong Zheng, Yangyang Li, Xiaoling Zheng

Open access · goldAbstract readReview
In one paragraph

Review in Journal of nanobiotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 56 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Nano-Based Technology in Glioblastoma.Molecules (Basel, Switzerland) · 2025
    Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. The role of cuproptosis in gastric cancer.Frontiers in immunology · 2024
    Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Weidong Fei *Department of Pharmacy, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, China.
Meng Zhang *Department of Pharmacy, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, China.
Xiaoyu FanSchool of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Sydney, 2006, Australia.
Yiqing YeDepartment of Pharmacy, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, China.
Mengdan ZhaoDepartment of Pharmacy, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, China.
Caihong ZhengDepartment of Pharmacy, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, China.
Yangyang LiKey Laboratory of Women's Reproductive Health Research of Zhejiang Province, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, China. 11526010@zju.edu.cn.
Xiaoling ZhengDepartment of Pharmacy, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, China. ekwefi@zju.edu.cn.
Women's Hospital, School of Medicine, Zhejiang University · CNUniversity of Sydney · AU

Funding

National Natural Science Foundation of China 81802587Natural Science Foundation of Zhejiang Province LQ20H300002Natural Science Foundation of Zhejiang Province Y19H040054
6 · The paper itself

Abstract

Metal sulfide nanomaterials (MeSNs) are a novel class of metal-containing nanomaterials composed of metal ions and sulfur compounds. During the past decade, scientists found that the MeSNs engineered by specific approaches not only had high biocompatibility but also exhibited unique physicochemical properties for cancer therapy, such as Fenton catalysis, light conversion, radiation enhancement, and immune activation. To clarify the development and promote the clinical transformation of MeSNs, the first section of this paper describes the appropriate fabrication approaches of MeSNs for medical science and analyzes the features and limitations of each approach. Secondly, we sort out the mechanisms of functional MeSNs in cancer therapy, including drug delivery, phototherapy, radiotherapy, chemodynamic therapy, gas therapy, and immunotherapy. It is worth noting that the intact MeSNs and the degradation products of MeSNs can exert different types of anti-tumor activities. Thus, MeSNs usually exhibit synergistic antitumor properties. Finally, future expectations and challenges of MeSNs in the research of translational medicine are spotlighted.

Indexed as

AnimalsAntineoplastic AgentsHumansHyperthermia, InducedImmunotherapyNanoparticlesNanostructuresNanotechnologyNeoplasmsPharmaceutical PreparationsPhototherapySulfidesTheranostic NanomedicineAntineoplastic AgentsPharmaceutical PreparationsSulfidesCancerFabricationMetal sulfideNanomaterialsTherapy

Identifiers

PMID33789653
PMCPMC8011210
OpenAlexW3149499589

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.