ArticleBMC veterinary research2021
Antimicrobial and antibiofilm potentials of cinnamon oil and silver nanoparticles against Streptococcus agalactiae isolated from bovine mastitis: new avenues for countering resistance.
Article in BMC veterinary research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 57 citations in OpenAlex.
- One Health Perspective on Antimicrobial Resistance in Bovine Mastitis Pathogens-A Narrative Review.Antibiotics (Basel, Switzerland) · 2026Review
- Harnessing biogenic nanoparticles for combating antibiotic resistance: green synthesis, mechanistic insights, and biotechnological applications.Frontiers in bioengineering and biotechnology · 2026Review
- Inhibitory effect of fluoroquinolones against biofilm formation by Staphylococcus aureus isolated from milk of dairy cows with mastitis.The Journal of veterinary medical science · 2026Article
- Association between animal welfare indicators and mastitis pathogens in bulk tank milk: the reality of small- and medium-scale dairy cattle farms in Italy.Frontiers in veterinary science · 2026Article
- Cinnamon-Mediated Silver Nanoparticles and Beta-Carotene Nanocarriers in Alginate Dressings for Wound Healing Applications.Gels (Basel, Switzerland) · 2025Article
- Essential Oils for Biofilm Control: Mechanisms, Synergies, and Translational Challenges in the Era of Antimicrobial Resistance.Antibiotics (Basel, Switzerland) · 2025Review
- Article
- Green Tea Extract (Antibiotics (Basel, Switzerland) · 2025Article
- Improving heat resilience in fattening rabbits: nutritional strategies for mitigation via regulating blood physiology, inflammation and antioxidant pathways.Frontiers in veterinary science · 2025Article
- Combination of Phytoactives in the Diet of Lactating Jersey Cows: Effects on Productive Efficiency, Milk Composition and Quality, Ruminal Environment, and Animal Health.Animals : an open access journal from MDPI · 2024Article
- From nature to nanomedicine: bioengineered metallic nanoparticles bridge the gap for medical applications.Discover nano · 2024Review
- Hexadecanamide alleviates Staphylococcus aureus-induced mastitis in mice by inhibiting inflammatory responses and restoring blood-milk barrier integrity.PLoS pathogens · 2023Article
- Antibacterial and Anti-Efflux Activities of Cinnamon Essential Oil against Pan and Extensive Drug-ResistantAntibiotics (Basel, Switzerland) · 2023Article
- Novel Perspectives on Food-Based Natural Antimicrobials: A Review of Recent Findings Published since 2020.Microorganisms · 2023Review
- The Antimicrobial Applications of Nanoparticles in Veterinary Medicine: A Comprehensive Review.Antibiotics (Basel, Switzerland) · 2023Review
- Plant Essential Oils as a Tool in the Control of Bovine Mastitis: An Update.Molecules (Basel, Switzerland) · 2023Review
- Alternatives to Antimicrobial Treatment in Bovine Mastitis Therapy: A Review.Antibiotics (Basel, Switzerland) · 2023Review
- Intramammary Ethno-Veterinary Formulation in Bovine Mastitis Treatment for Optimization of Antibiotic Use.Pathogens (Basel, Switzerland) · 2023Article
- Alternatives to antibiotics for treatment of mastitis in dairy cows.Frontiers in veterinary science · 2023Review
- Anti- and Pro-Oxidant Properties of Essential Oils against Antimicrobial Resistance.Antioxidants (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStreptococcus agalactiae (S. agalactiae) is a contagious pathogen of bovine mastitis. It has financial implications for the dairy cattle industry in certain areas of the world. Since antimicrobial resistance increases in dairy farms, natural antimicrobials from herbal origins and nanoparticles have been given more attention as an alternative therapy. Hence, this study reported the antimicrobial and antibiofilm potentials of cinnamon oil, silver nanoparticles (AgNPs), and their combination against multidrug-resistant (MDR) S. agalactiae recovered from clinical bovine mastitis in Egypt.
resultsOur findings revealed that 73% (146/200) of the examined milk samples collected from dairy cows with clinical mastitis were infected with Streptococci species. Of these, 9.59% (14/146) were identified as S. agalactiae and categorized as MDR. S. agalactiae isolates expressed four virulence genes (Hyl, cylE, scpB, and lmb) and demonstrated an ability to produce biofilms. Cinnamon oil showed high antimicrobial (MICs ≤0.063 μg /mL) and antibiofilm (MBIC
conclusionsThis is an in vitro preliminary approach that documented the antibiofilm potential of cinnamon oil and the inhibitory activity of cinnamon oil and its combination with AgNPs against MDR S. agalactiae recovered from clinical mastitis. Further in vivo studies should be carried out in animal models to provide evidence of concept for implementing these alternative candidates in the treatment of dairy farms infected by streptococcal mastitis in the future.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.