ArticleBMC cancer2021
Radiation-irritated skin and hyperpigmentation may impact the quality of life of breast cancer patients after whole breast radiotherapy.
Article in BMC cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 4 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Impact of breast cancer on body image: a systematic review and meta-analysis.Archives of women's mental health · 2026Pooled it
- A critical review of randomized controlled trials on topical corticosteroids for the prevention of radiation dermatitis in breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Pooled it
- Decrease of radiation-induced skin reactions in breast cancer patients by preventive application of film dressings-a systematic review.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2024Pooled it
- Preoperative Partial Breast Irradiation in Patients with Low-Risk Breast Cancer: A Systematic Review of Literature.Annals of surgical oncology · 2023Pooled it
- Quality of life following completion of surgery and chemoradiation among Sri Lankan women with breast cancer.BMC cancer · 2026Article
- Alginate and Chitosan-Based Hydrogels for the Treatment of Radiation Dermatitis.International wound journal · 2026Review
- Radiotherapy-Induced Skin Fibrosis: Pathophysiology, Emerging Therapeutics, and the Role of Dermatology.American journal of clinical dermatology · 2026Review
- Quality of life of breast cancer patients: A comparative study of survivors and patients undergoing radiotherapy in Morocco.Journal of education and health promotion · 2026Article
- Post-oncologic skin health: cutaneous recovery and rehabilitation after cancer treatments.Frontiers in oncology · 2026Review
- Willingness to Undergo Corrective Surgery After Breast-Conserving Surgery in Chinese Patients with Breast Deformities: A Single-Center Study.Breast cancer (Dove Medical Press) · 2026Article
- Improving Patient Awareness on Breast Cancer Radiotherapy Side Effects and Survivorship: A Patient Education Intervention at the Mays Cancer Center.Journal of cancer education : the official journal of the American Association for Cancer Education · 2025Article
- Review
- Correction of breast deformities after breast-conserving surgery in Chinese women with breast cancer: a narrative review.Frontiers in oncology · 2025Review
- Validation of the Skin Symptom Assessment (SSA) questionnaire for the evaluation of radiation dermatitis in breast cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Mepitel film for the prevention of radiation dermatitis: A comprehensive review of its efficacy, side effects, physics measurements, patient- and clinician-reported outcomes.Asia-Pacific journal of oncology nursing · 2024Review
- Cosmetic considerations after breast cancer treatment.Archives of dermatological research · 2024Review
- Disparities in quality of life among patients with breast cancer based on surgical methods: a cross-sectional prospective study.Scientific reports · 2024Article
- The Impact of Dermatologic Adverse Events on the Quality of Life of Oncology Patients: A Review of the Literature.American journal of clinical dermatology · 2024Review
- Ledderhose's Disease: An Up-to-Date Review of a Rare Non-Malignant Disorder.Clinics and practice · 2023Review
- Cicaderma® in radiation-related dermatitis of breast cancer: Results from the multicentric randomised phase III CICA-RT.Clinical and translational radiation oncology · 2023Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study aimed to investigate skin condition, quality of life, and psychological impact of breast cancer patients after radiation therapy. We designed and administered a questionnaire to breast cancer survivors for better understanding the skin sequelae after radiation therapy.
methodsThis study performed an anonymous online survey. Invitation join was posted in Facebook groups for Breast Cancer. Content of the questionnaire included basic information and a three-point scale on the degree of skin dryness, sweating, hotness sensation, itchy sensation, presence of pigment deposition, history of severe skin disorder, psychological impact, and quality of life after radiotherapy. Categorical variables were summarized using counts and percentages, and then Mantel-Haenszel chi-square tests, multiple correspondence analysis, Wald chi-square statistics, and logistic regression analyses were performed; P < 0.05 was considered statistically significant.
resultsIn total, 421 breast cancer survivors completed the questionnaire. Among them, 331 (78.62%) reported rarely sweating; 340 (80.76%) reported dry skin; 184 (43.71%) reported itchy skin in addition to dry skin; 336 (79.81%) had severe or mild skin color deposition; and 76 (18.05%) had eczema or contact dermatitis. Dry skin problems were caused by absent sweating and skin dryness in the irradiated skin area, post-RT severe skin disorders, and skin color deposition. Compared with patients sweating normally in the radiation field, patients with absent sweating and hotness sensation in the radiation field had a higher risk of depression.
conclusionsThis study showed that breast cancer patients after whole breast radiotherapy may experience skin dryness, hypersensitivity and hyper pigmentation in the irradiated skin area. These "radiation-irritated skin" lesions may induce depressive psychological status and impact the quality of life in breast cancer patients after whole breast radiotherapy.
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