SynthesisBMC pregnancy and childbirth2021
Risk factors for non-adherent retained placenta after vaginal delivery: a systematic review.
Synthesis in BMC pregnancy and childbirth, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prophylactic antibiotics for manual removal of retained placenta in vaginal birth.The Cochrane database of systematic reviews · 2024Pooled it
- A meta-analysis of obstetric and neonatal outcomes in patients after treatment of hysteroscopic adhesiolysis.Frontiers in endocrinology · 2023Pooled it
- Anesthetic strategies for manual removal of retained placenta: an observational cohort study at a university referral center.Journal of anesthesia, analgesia and critical care · 2026Article
- Article
- Association between obstetric comorbidity index and complications of vaginal delivery: a large cross-sectional study from China.BMC pregnancy and childbirth · 2025Article
- The experience of manual removal of placenta in women with retained placenta: a qualitative study.BMC pregnancy and childbirth · 2025Article
- Using Comparative Transcriptomics and Histology to Identify Significant Differentially Expressed Genes Associated with Retained Placenta in Humans and Rhesus Macaques (Macaca mulatta).Journal of the American Association for Laboratory Animal Science : JAALAS · 2025Article
- Novel risk factors associated with retained placenta after vaginal birth.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025Article
- Article
- Retained non-previa placenta in the era of "placenta accreta spectrum": a report of two cases managed expectantly and a proposed plan for management.Frontiers in medicine · 2025Article
- The safety and effectiveness of ultrasound-guided instrumental removal of retained placenta after failed removal immediately after delivery.Case reports in perinatal medicine · 2025Article
- Maternal Morbidity Associated with Early Preterm Birth in Low-Risk Singleton Pregnancies.Journal of clinical medicine · 2024Article
- Evaluation of the Management and Outcome of Patients with Retained Products of Conception after Gestational Week 23+0: A Retrospective Cohort Study.Journal of clinical medicine · 2024Article
- Surgical Conservative Management of a Retained Placenta after Angular Pregnancy, a Case Report and Literature Review.Diagnostics (Basel, Switzerland) · 2023Article
- Severe maternal morbidity following stillbirth in Western Australia 2000-2015: a population-based study.Archives of gynecology and obstetrics · 2023Article
- Maternal morbidity under an absolute abortion ban: insights from a 6-year case series of fatal fetal malformations in El Salvador.AJOG global reports · 2023Article
- Risk factors and recurrence of cause-specific postpartum hemorrhage: A population-based study.PloS one · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRetained placenta represents a cause of maternal morbidity and mortality affecting 0.5-3% of all vaginal deliveries. The unpredictability of this condition makes difficult to develop predictive and preventive strategies to apply in clinical practice. This analysis collected and analyzed all known risk factors related to this obstetric complication.
methodsA systematic literature review for all original research articles published between 1990 and 2020 was performed. Observational studies about retained placenta risk factors published in English language were considered eligible. Conference abstracts, untraceable articles and studies focused on morbidly adherent placenta were excluded. The included articles were screened to identify study design, number of enrolled patients and retained placenta risk factors investigated. All stages of the revision followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Statement.
resultsThirty-five studies met the inclusion criteria. The reported retained placenta prevalence ranged from 0.5 to 4.8%. Maternal age, previous cesarean sections, previous dilation and curettage, previous retained placenta, labor induction, resulted as the most recurrent, independent risk factors for retained placenta. Previous estro-progestins therapy, morphological placental features (weight, shape, insertion of umbilical cord, implantation site), endometriosis, Assisted Reproductive Technologies, Apgar score are fascinating new proposal risk factors.
conclusionsOld and new data are not enough robust to draw firm conclusions. Prospective and well-designed studies, based on a well agreed internationally retained placenta definition, are needed in order to clarify this potential dramatic and life-threatening condition.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.