Evidence map›Paper›PMID 33789162›Full record

ArticleThe Journal of biological chemistry

Phosphodiesterase 1C integrates store-operated calcium entry and cAMP signaling in leading-edge protrusions of migrating human arterial myocytes.

Paulina Brzezinska, Nicholas J Simpson, Fabien Hubert, Ariana N Jacobs, M Bibiana Umana, Jodi L MacKeil, Jonah Burke-Kleinman, Darrin M Payne, Alastair V Ferguson, Donald H Maurice

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Paulina BrzezinskaDepartment of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada.
Nicholas J SimpsonDepartment of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada.
Fabien HubertDepartment of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada.
Ariana N JacobsDepartment of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada.
M Bibiana UmanaDepartment of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada.
Jodi L MacKeilDepartment of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada.
Jonah Burke-KleinmanDepartment of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada.
Darrin M PayneDepartment of Surgery, Queen's University, Kingston, Ontario, Canada.
Alastair V FergusonDepartment of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada.
Donald H MauriceDepartment of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada. Electronic address: mauriced@queensu.ca.
Queen's University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In addition to maintaining cellular ER Ca

Indexed as

Signal TransductionArteriesBiological TransportCalciumCell MovementCyclic AMPCyclic Nucleotide Phosphodiesterases, Type 1Gene Expression Regulation, EnzymologicHumansKineticsMuscle CellsCalciumCyclic AMPCyclic Nucleotide Phosphodiesterases, Type 1adenylate cyclasecalciumcyclic AMPhuman arterial smooth muscle cellsphosphodiesterase 1Cphosphodiesterasesstore-operated calcium entry

Identifiers

PMID33789162
PMCPMC8095186
OpenAlexW3150412066

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.