Evidence map›Paper›PMID 33788987›Full record

Trial reportJournal of biophotonics2021

Light emitting diode-red light for reduction of post-surgical scarring: Results from a dose-ranging, split-face, randomized controlled trial.

Alana Kurtti, Julie K Nguyen, Jeremy Weedon, Andrew Mamalis, Yi Lai, Natasha Masub, Amaris Geisler, Daniel M Siegel, Jared R Jagdeo

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of biophotonics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06033430 (The Effectiveness of Dry Needling in Treating Linear Hypertrophic Scar Tissue), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06033430 naunknown statusnot on this mapstarted 2023, after this paper: background citation

The Effectiveness of Dry Needling in Treating Linear Hypertrophic Scar Tissue: a Randomized Sham-controlled Trial

TypeinterventionalSponsorIran University of Medical SciencesRan2023 to 2025Enrolled80ConditionsScar Tissue, Hypertrophic Scar, Hypertrophic Scar of Upper Arm (Disorder), Hypertrophic Surgical ScarArmsTrue dry needling, Sham dry needling
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Alana KurttiRutgers Robert Wood Johnson Medical School, Piscataway, New Jersey, USA.
Julie K NguyenDermatology Service, VA New York Harbor Healthcare System, Brooklyn, New York, USA.
Jeremy WeedonOffice of the SVP for Research, SUNY Downstate Health Sciences University, Brooklyn, New York, USA.
Andrew MamalisDepartment of Dermatology, The Permanente Medical Group, Modesto, California, USA.
Yi LaiDermatology Service, VA New York Harbor Healthcare System, Brooklyn, New York, USA.
Natasha MasubDermatology Service, VA New York Harbor Healthcare System, Brooklyn, New York, USA.
Amaris GeislerDermatology Service, VA New York Harbor Healthcare System, Brooklyn, New York, USA.
Daniel M SiegelDermatology Service, VA New York Harbor Healthcare System, Brooklyn, New York, USA.ORCID 0000-0002-3918-9483
Jared R JagdeoDermatology Service, VA New York Harbor Healthcare System, Brooklyn, New York, USA.ORCID 0000-0002-7619-7650
SUNY Downstate Health Sciences University · USKaiser Permanente Modesto Medical Center and Medical Offices · USRutgers, The State University of New Jersey · US

Funding

Light Emitting Diod-Red Light Phototherapy for Skin FibrosisK23GM117309 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI JAGDEO, JARED R · 2016 to 2019
$777k
NIGMS NIH HHS K23 GM117309
6 · The paper itself

Abstract

Scarring has significant esthetic and functional consequences for patients. A need exists for anti-scarring therapeutics. Light emitting diode-red light (LED-RL) has been shown to modulate skin fibrosis. The aim of this study is to evaluate the safety and efficacy of LED-RL to reduce post-operative scarring. Cutaneous Understanding of Red-light Efficacy on Scarring was a randomized, mock-controlled, single-blind, dose-ranging, split-face phase II clinical trial. Starting 1 week post-surgery, patients received LED-RL irradiation and temperature-controlled mock therapy to incision sites at fluences of 160, 320 or 480 J/cm

Indexed as

CicatrixSkinHumansLightPhototherapySingle-Blind MethodTreatment Outcomelow level light therapyphototherapyscarringwound healing

Identifiers

PMID33788987
PMCPMC8919713
OpenAlexW3145811667

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.